ZFYVE1

Description		zinc finger FYVE-type containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Mitochondrion Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Lipid Droplet Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Perinuclear Region Of Cytoplasm Extrinsic Component Of Omegasome Membrane Omegasome
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Metal Ion Binding
	Biological Process	Cellular Response To Starvation Macroautophagy Host-mediated Activation Of Viral Genome Replication Lipid Droplet Formation
Pathways
Drugs
Diseases
GWAS		LDL cholesterol levels ( 32203549) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Refractive error ( 32231278) Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous) ( 28628665)
Novel Interacting Genes		5 novel interacting genes: APP BCL2L1 FGFR1 MAGOHB PRKCH
Interacting Genes		5 interacting genes: APP BCL2L1 FGFR1 MAGOHB PRKCH
Entrez ID		53349
HPRD ID		12017
Ensembl ID		ENSG00000165861
Uniprot IDs		Q9HBF4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Extrinsic Apoptotic Signaling Pathway Protein Serine/threonine Kinase Binding Regulation Of Cell Junction Assembly Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Amyloid-beta Complex Growth Cone Lamellipodium Negative Regulation Of Metabolic Process Negative Regulation Of Gene Expression Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Neuron Differentiation Regulation Of Apoptotic Process Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway Apoptotic Process In Bone Marrow Cell Positive Regulation Of Mitotic Cell Cycle DNA Replication Positive Regulation Of Parathyroid Hormone Secretion Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of Synapse Assembly Regulation Of Growth Positive Regulation Of Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Signal Transduction Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Positive Regulation Of Protein Metabolic Process Developmental Maturation Regulation Of Chemotaxis Axon Midline Choice Point Recognition Intracellular Signaling Cassette Positive Regulation Of Chemotaxis Regulation Of Cell Population Proliferation Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Neuron Differentiation Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Cell Maturation Positive Regulation Of Endothelin Production Negative Regulation Of Macromolecule Biosynthetic Process Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Postsynapse Organization Cell Development Negative Regulation Of Biosynthetic Process
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