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PLCL1
Description
phospholipase C like 1 (inactive)
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Molecular Function
Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity
Phospholipase C Activity
Phosphoric Diester Hydrolase Activity
Biological Process
Lipid Metabolic Process
Signal Transduction
Gamma-aminobutyric Acid Signaling Pathway
Regulation Of Synaptic Transmission, GABAergic
Intracellular Signal Transduction
Phosphatidylinositol Metabolic Process
Phosphatidylinositol-mediated Signaling
Release Of Sequestered Calcium Ion Into Cytosol
Negative Regulation Of Cold-induced Thermogenesis
Pathways
Drugs
Quinacrine
Diseases
GWAS
A body shape index (
34021172
)
Adult body size (
32376654
)
Alcohol consumption (
23743675
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
)
Allergy (
27182965
)
Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) (
31835028
)
Appendicular lean mass (
33097823
)
Asthma (
31361310
32296059
)
Autism spectrum disorder or schizophrenia (
28540026
)
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Brain cytoarchitecture (
20308991
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Central retinal arteriolar equivalent (
31597446
)
Chin dimples (
27182965
)
Chronotype (
30696823
)
Coronary artery disease (
26708285
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Crohn's disease (
28067908
21102463
)
Dermatomyositis (
23983088
)
Educational attainment (
23722424
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Hip bone size (
18776929
)
Intracranial aneurysm (
18997786
)
Low high density lipoprotein cholesterol levels (
26879886
)
Menarche (age at onset) (
21102462
27182965
)
Mood instability (
31168069
)
Morning person (
30696823
)
Morning vs. evening chronotype (
26835600
)
Neutrophil count (
21507922
)
Rheumatoid arthritis (
30891314
32868391
)
Schizophrenia (
25056061
29483656
30285260
)
Self-reported allergy (
23817569
)
Serum alkaline phosphatase levels (
33547301
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Sun-seeking behavior (
32920024
)
Systemic lupus erythematosus (
28714469
33536424
)
Total body bone mineral density (
29304378
)
Ulcerative colitis (
23128233
)
Urinary sodium excretion (
31409800
)
Waist circumference adjusted for body mass index (
34021172
)
Novel Interacting Genes
1 novel interacting genes:
CTLA4
Interacting Genes
1 interacting genes:
CTLA4
Entrez ID
5334
HPRD ID
07041
Ensembl ID
ENSG00000115896
Uniprot IDs
Q15111
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Complex Involved In Cell Adhesion
Negative Regulation Of Regulatory T Cell Differentiation
Negative Regulation Of B Cell Proliferation
Clathrin-coated Endocytic Vesicle
Regulation Of Regulatory T Cell Differentiation
Negative Regulation Of B Cell Activation
Regulation Of B Cell Proliferation
Negative Regulation Of Lymphocyte Differentiation
B Cell Receptor Signaling Pathway
Negative Regulation Of T Cell Differentiation
Negative Regulation Of T Cell Proliferation
Negative Regulation Of Leukocyte Proliferation
Negative Regulation Of Lymphocyte Proliferation
T Cell Receptor Signaling Pathway
Negative Regulation Of Hemopoiesis
Negative Regulation Of Mononuclear Cell Proliferation
Regulation Of B Cell Activation
Negative Regulation Of T Cell Activation
Negative Regulation Of Leukocyte Cell-cell Adhesion
Antigen Receptor-mediated Signaling Pathway
Negative Regulation Of Lymphocyte Activation
Regulation Of T Cell Proliferation
Regulation Of T Cell Differentiation
Negative Regulation Of Cell Activation
Regulation Of Lymphocyte Differentiation
Negative Regulation Of Cell-cell Adhesion
Negative Regulation Of Leukocyte Activation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Mononuclear Cell Proliferation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Leukocyte Proliferation
Negative Regulation Of Cell Development
Adaptive Immune Response
Negative Regulation Of Cell Adhesion
Immune Response-activating Signaling Pathway
External Side Of Plasma Membrane
Tagcloud
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