PLAG1

Description		PLAG1 zinc finger
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Body Nuclear Speck
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Gland Morphogenesis Multicellular Organism Growth Organ Growth Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glial Cell Proliferation Prostate Gland Growth
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 31043758) Heel bone mineral density ( 30598549) Height ( 19343178 31562340 28552196 25429064 25282103 20189936 19893584 19396169 18391951) Hip circumference adjusted for BMI ( 25673412 34021172) Monocyte count ( 32888494) Plateletcrit ( 32888494) Refractive error ( 32231278)
Novel Interacting Genes		5 novel interacting genes: KPNA2 PIAS1 PIAS2 PIAS4 SMAD3
Interacting Genes		5 interacting genes: KPNA2 PIAS1 PIAS2 PIAS4 SMAD3
Entrez ID		5324
HPRD ID		04321
Ensembl ID		ENSG00000181690
Uniprot IDs		Q6DJT9
PDB IDs
Enriched GO Terms of Interacting Partners?		SUMO Ligase Activity SUMO Transferase Activity Protein Sumoylation Ubiquitin Protein Ligase Binding PML Body Transcription Coregulator Activity Positive Regulation Of Protein Sumoylation Transcription Corepressor Activity Regulation Of Protein Sumoylation SMAD Protein Signal Transduction Chromatin Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Lung Blood Pressure Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Mineralocorticoid Receptor Binding Regulation Of RNA Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Post-translational Protein Modification Limb Epidermis Development Protein Modification By Small Protein Conjugation Regulation Of DNA Recombination Nucleoplasm DNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Sterol Response Element Binding Zinc Ion Binding Paraxial Mesoderm Morphogenesis Cell Surface Receptor Signaling Pathway Signal Transduction Intracellular Signaling Cassette Viral Penetration Into Host Nucleus DNA Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Lung Blood Pressure DNA-binding Transcription Factor Binding Post-translational Protein Modification Positive Regulation Of Keratinocyte Apoptotic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Biosynthetic Process
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