SERPINI1

Description		serpin family I member 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasmic Vesicle Secretory Granule Lumen Neuronal Cell Body Perikaryon Cytoplasmic Vesicle Lumen Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity
	Biological Process	Central Nervous System Development Peripheral Nervous System Development Positive Regulation Of Neuron Projection Development
Pathways
Drugs
Diseases
GWAS		Eye color (saturation) ( 30664655) Fast beta electroencephalogram ( 28070124) Heart rate ( 23534349) Height ( 18391951) Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483) Skin, hair and eye pigmentation (multivariate analysis) ( 30664655)
Novel Interacting Genes		3 novel interacting genes: PLAT PLG TSC2
Interacting Genes		3 interacting genes: PLAT PLG TSC2
Entrez ID		5274
HPRD ID		03901
Ensembl ID		ENSG00000163536
Uniprot IDs		A0A0S2Z455 Q99574
PDB IDs		3F02 3F5N 3FGQ
Enriched GO Terms of Interacting Partners?		Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Trans-synaptic Signaling By BDNF Negative Regulation Of Fibrinolysis Trans-synaptic Signaling, Modulating Synaptic Transmission Regulation Of Fibrinolysis Fibrinolysis Positive Regulation Of Blood Coagulation Positive Regulation Of Coagulation Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Negative Regulation Of Coagulation Positive Regulation Of Wound Healing Negative Regulation Of Wound Healing Regulation Of Hemostasis Regulation Of Blood Coagulation Schaffer Collateral - CA1 Synapse Coagulation Blood Coagulation Hemostasis Serine-type Peptidase Activity Regulation Of Wound Healing Serine-type Endopeptidase Activity Regulation Of Response To Wounding Protein Processing TSC1-TSC2 Complex Positive Regulation Of Fibrinolysis Prevention Of Polyspermy Serine Protease Inhibitor Complex Regulation Of Body Fluid Levels Protein Maturation Trans-synaptic Signaling Negative Regulation Of Plasminogen Activation Synaptic Signaling Signaling Receptor Binding Protein Antigen Binding Extracellular Matrix Regulation Of Fertilization Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Plasminogen Activation Peptidase Activity Negative Regulation Of Mitophagy Anoikis Smooth Muscle Cell Migration Modulation Of Chemical Synaptic Transmission Trophoblast Giant Cell Differentiation Regulation Of Plasminogen Activation Apolipoprotein Binding Glutamatergic Synapse Negative Regulation Of Protein Metabolic Process Labyrinthine Layer Blood Vessel Development
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