SERPINB6

Description		serpin family B member 6
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Secretory Granule Membrane Extracellular Matrix Extracellular Exosome Tertiary Granule Membrane Serine Protease Inhibitor Complex Ficolin-1-rich Granule Membrane
	Molecular Function	Protease Binding Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity
	Biological Process	Sensory Perception Of Sound Cellular Response To Osmotic Stress
Pathways		Neutrophil degranulation Dissolution of Fibrin Clot
Drugs		Drotrecogin alfa
Diseases
GWAS		Chronic lymphocytic leukemia ( 26956414) Crohn's disease ( 32581322)
Novel Interacting Genes		8 novel interacting genes: F10 F2 KLK2 MYCBP2 PLAU PLG PROC SUMO2
Interacting Genes		8 interacting genes: F10 F2 KLK2 MYCBP2 PLAU PLG PROC SUMO2
Entrez ID		5269
HPRD ID		01413
Ensembl ID		ENSG00000124570
Uniprot IDs		A0A024QZX5 A0A087X1N8 A0A2R8YD12 P35237
PDB IDs
Enriched GO Terms of Interacting Partners?		Serine-type Peptidase Activity Serine-type Endopeptidase Activity Coagulation Blood Coagulation Hemostasis Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Negative Regulation Of Coagulation Peptidase Activity Negative Regulation Of Fibrinolysis Negative Regulation Of Wound Healing Regulation Of Hemostasis Regulation Of Blood Coagulation Regulation Of Fibrinolysis Regulation Of Body Fluid Levels Fibrinolysis Positive Regulation Of Blood Coagulation Positive Regulation Of Coagulation Regulation Of Wound Healing Protein Metabolic Process Regulation Of Response To Wounding Proteolysis Positive Regulation Of Wound Healing Endopeptidase Activity Extracellular Space Golgi Lumen External Side Of Plasma Membrane Hydrolase Activity Macromolecule Metabolic Process Protein Processing Extracellular Region Biological Process Involved In Interaction With Symbiont Zymogen Activation Regulation Of Biological Quality Endoplasmic Reticulum Lumen Protein Maturation Regulation Of Proteolysis Regulation Of Locomotion Urokinase Plasminogen Activator Signaling Pathway Negative Regulation Of Multicellular Organismal Process Blood Microparticle Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Receptor Ligand Activity Positive Regulation Of Cell Migration Negative Regulation Of Proteolysis Thrombospondin Receptor Activity Positive Regulation Of Cell Motility Regulation Of Smooth Muscle Cell-matrix Adhesion Trans-synaptic Signaling By BDNF Positive Regulation Of Fibrinolysis
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