ATP6V1B1

Description		ATPase H+ transporting V1 subunit B1
Image		No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Cytoplasm Cytosol Plasma Membrane Microvillus Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Extracellular Exosome Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Proton Transmembrane Transporter Activity Protein-containing Complex Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Ossification Renal Water Homeostasis Renal Sodium Ion Transport Prostaglandin Metabolic Process Monoatomic Ion Transport Regulation Of PH Vacuolar Acidification Sensory Perception Of Sound Regulation Of Gene Expression Regulation Of Macroautophagy Adult Behavior Renal Sodium Excretion Olfactory Behavior Inner Ear Morphogenesis PH Reduction ATP Metabolic Process Chloride Ion Homeostasis Calcium Ion Homeostasis Potassium Ion Homeostasis Vacuolar Proton-transporting V-type ATPase Complex Assembly Renal Tubular Secretion Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases		Distal renal tubular acidosis (RTA type 1)
GWAS		Acne (severe) ( 24927181) Urate levels ( 31578528)
Novel Interacting Genes		5 novel interacting genes: ACTN4 KDM1A NHERF1 STX1A SUV39H1
Interacting Genes		5 interacting genes: ACTN4 KDM1A NHERF1 STX1A SUV39H1
Entrez ID		525
HPRD ID		01887
Ensembl ID		ENSG00000116039
Uniprot IDs		P15313
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoside Binding Transmembrane Transporter Binding Organelle Localization Muscle Cell Development Positive Regulation Of Sodium:proton Antiporter Activity Protein-containing Complex Regulation Of Sodium Ion Transport Identical Protein Binding Myosin Head/neck Binding Amide Transport Peptide Transport Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex ENoSc Complex Type 2 Metabotropic Glutamate Receptor Binding Regulation Of Cell Size Type 3 Metabotropic Glutamate Receptor Binding Regulation Of Renal Phosphate Excretion Dopamine Receptor Binding Renal Phosphate Ion Absorption Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Establishment Of Organelle Localization Vesicle Transport Along Actin Filament ATP-dependent Protein Binding Endomembrane System Response To Gravity Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Chloride Channel Inhibitor Activity Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Histone H3K9 Trimethyltransferase Activity Histone H3K9me2 Methyltransferase Activity RDNA Heterochromatin Formation Regulation Of DNA Repair RDNA Heterochromatin Microvillus Organization Regulation Of Cellular Component Size Maintenance Of Epithelial Cell Apical/basal Polarity Bile Acid Secretion Microvillus Assembly Establishment Of Golgi Localization Channel Activator Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Beta-2 Adrenergic Receptor Binding Phospholipase C-activating Dopamine Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Chloride Channel Regulator Activity Gamma-aminobutyric Acid Import
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