GET4

Description		guided entry of tail-anchored proteins factor 4
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol BAT3 Complex
	Molecular Function	Protein Binding Protein-folding Chaperone Binding Protein Carrier Chaperone
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Protein Stability ERAD Pathway Maintenance Of Unfolded Protein Protein Insertion Into ER Membrane Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		PR interval ( 32439900)
Novel Interacting Genes		30 novel interacting genes: AIRIM AKT1 ATP5PD CAPNS1 CDKN1A CEBPA CEP126 DNAAF5 DUSP21 EEF1G ENKD1 FBN1 FBXO7 FLYWCH2 GIT2 KAT5 KIFC2 KRTAP9-3 NUP85 PLK1 PRKAB2 PRKCSH PTMS SDCBP SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2
Interacting Genes		30 interacting genes: AIRIM AKT1 ATP5PD CAPNS1 CDKN1A CEBPA CEP126 DNAAF5 DUSP21 EEF1G ENKD1 FBN1 FBXO7 FLYWCH2 GIT2 KAT5 KIFC2 KRTAP9-3 NUP85 PLK1 PRKAB2 PRKCSH PTMS SDCBP SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2
Entrez ID		51608
HPRD ID		12909
Ensembl ID		ENSG00000239857
Uniprot IDs		Q7L5D6
PDB IDs		6AU8 7RU9 7RUA 7RUC
Enriched GO Terms of Interacting Partners?		Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Localization Microtubule Cytoskeleton Organization Involved In Mitosis Establishment Of Mitotic Spindle Orientation Establishment Of Spindle Localization Response To Nutrient Levels Spindle Localization Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Localization To Nucleus Establishment Of Protein Localization To Organelle Carbohydrate Homeostasis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Glucose Homeostasis Protein Localization To Endoplasmic Reticulum Regulation Of Macroautophagy Microtubule-based Process Positive Regulation Of Protein Modification Process
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