NBAS

Description		NBAS subunit of NRZ tethering complex
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Dsl1/NZR Complex
	Molecular Function	SNARE Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Pathways		COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Familial squamous cell lung carcinoma ( 29924316) Intake of sweets ( 31005972) LDL peak particle diameter (total fat intake interaction) ( 26112879) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Recalcitrant atopic dermatitis ( 25935106) Response to platinum-based chemotherapy (carboplatin) ( 21844884) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Systemising ( 31508503)
Novel Interacting Genes		2 novel interacting genes: HSPB1 OLFM2
Interacting Genes		2 interacting genes: HSPB1 OLFM2
Entrez ID		51594
HPRD ID		10473
Ensembl ID		ENSG00000151779
Uniprot IDs		A2RRP1 G1UI26
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Kinase C Signaling Regulation Of Protein Kinase C Signaling Positive Regulation Of Endothelial Cell Chemotaxis Protein Transport Along Microtubule Anterograde Axonal Protein Transport Protein Kinase C Inhibitor Activity Contractile Muscle Fiber Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation Positive Regulation Of Smooth Muscle Cell Differentiation Protein Localization To Synapse Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Protein Transport Protein Folding Chaperone Establishment Of Protein Localization Protein Kinase C Binding Platelet Aggregation Axon Cytoplasm Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Interleukin-1 Beta Production Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Axonal Transport Positive Regulation Of Developmental Process Anterograde Axonal Transport Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cornified Envelope Protein Refolding Proteasome Complex Extracellular Space Homotypic Cell-cell Adhesion Regulation Of Smooth Muscle Cell Differentiation AMPA Glutamate Receptor Complex Positive Regulation Of Interleukin-1 Production Positive Regulation Of Muscle Cell Differentiation Response To Unfolded Protein Protein Localization To Cell Junction Response To Heat Axo-dendritic Transport Intracellular Protein Localization Regulation Of Translational Initiation Regulation Of Interleukin-1 Production Unfolded Protein Binding Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Endothelial Cell Migration Ubiquitin Binding Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Interleukin-1 Beta Production Protein Localization To Extracellular Region
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