AZIN1

Description		antizyme inhibitor 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Catalytic Activity Ornithine Decarboxylase Activity Protein Binding Ornithine Decarboxylase Activator Activity
	Biological Process	Polyamine Biosynthetic Process Putrescine Biosynthetic Process From Arginine, Via Ornithine Negative Regulation Of Protein Catabolic Process Positive Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC)
Drugs
Diseases
GWAS		Airway imaging phenotypes ( 26030696) Apolipoprotein A1 levels ( 32203549) Granulocyte count ( 27863252) HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Neutrophil count ( 27863252) PR interval ( 32439900) QT interval ( 24952745) Serum alkaline phosphatase levels ( 33547301) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) TPE interval (resting) ( 32386560) Waist circumference adjusted for body mass index ( 28552196) White blood cell count ( 32888494)
Novel Interacting Genes		1 novel interacting genes: SORCS3
Interacting Genes		7 interacting genes: ABCC2 ADSS1 BMAL1 CDKN2A FANCA FANCC KHDRBS1
Entrez ID		51582
HPRD ID		07443
Ensembl ID		ENSG00000155096
Uniprot IDs		A0A804HLH4 B3KTF6 O14977
PDB IDs		4ZGZ
Enriched GO Terms of Interacting Partners?		Fanconi Anaemia Nuclear Complex Cellular Senescence Ligase Inhibitor Activity Bilirubin Transmembrane Transporter Activity Bilirubin Transport Interstrand Cross-link Repair Grb2-Sos Complex
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