PDE1B

Description		phosphodiesterase 1B
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GO Annotations	Cellular Component	Cytosol Neuronal Cell Body
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Calmodulin-dependent Cyclic-nucleotide Phosphodiesterase Activity Protein Binding Calmodulin Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity Calcium- And Calmodulin-regulated 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Regulation Of Neurotransmitter Levels Response To Amphetamine Apoptotic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Locomotory Behavior Visual Learning Monocyte Differentiation Cellular Response To Macrophage Colony-stimulating Factor Stimulus Regulation Of Dopamine Metabolic Process Serotonin Metabolic Process Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Pathways		Cam-PDE 1 activation cGMP effects G alpha (s) signalling events
Drugs		Caffeine Caffeine Nicardipine Felodipine Bepridil S,S-(2-Hydroxyethyl)Thiocysteine Trapidil
Diseases
GWAS		Post bronchodilator FEV1 in COPD ( 26634245)
Novel Interacting Genes		1 novel interacting genes: PRIM1
Interacting Genes		2 interacting genes: POT1 UBE3A
Entrez ID		5153
HPRD ID		01388
Ensembl ID		ENSG00000123360
Uniprot IDs		A0A024RB59 B3KX78 B4DK72 Q01064 Q7Z364
PDB IDs		1LXR 1TAZ 4NPV 4NPW 5B25 5UOY 5UP0 5W6E
Enriched GO Terms of Interacting Partners?
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