HSD17B7

Description		hydroxysteroid 17-beta dehydrogenase 7
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Oxidoreductase Activity 5-alpha-androstane-3-beta,17-beta-diol Dehydrogenase (NADP+) Activity
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Estrogen Biosynthetic Process Nervous System Development Brain Development Androgen Metabolic Process Cell Differentiation Embryonic Organ Development Embryonic Skeletal System Development
Pathways		Cholesterol biosynthesis Cholesterol biosynthesis via lathosterol
Drugs		NADH
Diseases
GWAS		Dupuytren's disease ( 28886342)
Novel Interacting Genes		7 novel interacting genes: BRSK1 CA1 DTYMK GORAB GPAT4 PBRM1 VKORC1
Interacting Genes		7 interacting genes: BRSK1 CA1 DTYMK GORAB GPAT4 PBRM1 VKORC1
Entrez ID		51478
HPRD ID		05996
Ensembl ID		ENSG00000132196
Uniprot IDs		P56937
PDB IDs
Enriched GO Terms of Interacting Partners?		DTMP Kinase Activity DUDP Biosynthetic Process DTDP Biosynthetic Process Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Cyanamide Hydratase Activity Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Glycerol-3-phosphate O-acyltransferase Activity Microtubule Cytoskeleton Organization Involved In Establishment Of Planar Polarity Distal Axon Arylesterase Activity Thymidine Biosynthetic Process DTTP Biosynthetic Process Synaptic Vesicle Cycle Hydro-lyase Activity Thymidine Metabolic Process Pyrimidine Deoxyribonucleotide Biosynthetic Process Regulation Of Synaptic Vesicle Clustering Glandular Epithelial Cell Maturation Response To Fructose Quinone Binding Regulation Of Synaptic Vesicle Priming Cholinergic Synapse Lysophosphatidic Acid Acyltransferase Activity CDP-diacylglycerol Biosynthetic Process Columnar/cuboidal Epithelial Cell Maturation Carbonate Dehydratase Activity Pyrimidine Nucleoside Metabolic Process 2'-deoxyribonucleotide Biosynthetic Process Nucleoside Diphosphate Kinase Activity Deoxyribonucleotide Biosynthetic Process Nucleoside Diphosphate Biosynthetic Process RSC-type Complex Peptidyl-glutamic Acid Modification Regulation Of Body Fluid Levels Vitamin K Metabolic Process CDP-diacylglycerol Metabolic Process 1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Biosynthetic Process
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