PLA1A

Description		phospholipase A1 member A
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Extracellular Region Extracellular Space
	Molecular Function	Phospholipase A1 Activity Lipase Activity Hydrolase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Lipid Metabolic Process Phosphatidylserine Metabolic Process Lipid Catabolic Process Phosphatidylserine Acyl-chain Remodeling
Pathways		Acyl chain remodelling of PS
Drugs
Diseases
GWAS
Novel Interacting Genes		3 novel interacting genes: ANXA2 APP CD47
Interacting Genes		3 interacting genes: ANXA2 APP CD47
Entrez ID		51365
HPRD ID		07078
Ensembl ID		ENSG00000144837
Uniprot IDs		G5E9W0 Q53H76
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Endocytosis Regulation Of Endocytosis Regulation Of Receptor Internalization Positive Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Endocytosis Myeloid Cell Development Cell Surface Regulation Of Vesicle-mediated Transport Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Serine-type Endopeptidase Inhibitor Activity Response To Interleukin-1 Cell Death Apoptotic Process Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Transport Cell Adhesion Programmed Cell Death Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Mononuclear Cell Migration Regulation Of Response To Calcium Ion Regulation Of Type II Interferon Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport Positive Regulation Of Cellular Component Organization AnxA2-p11 Complex PCSK9-AnxA2 Complex Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Hemopoiesis Acetylcholine Receptor Activator Activity Positive Regulation Of Inflammatory Response Regulation Of Tumor Necrosis Factor Production Regulation Of Interleukin-6 Production Positive Regulation Of Supramolecular Fiber Organization Lipoprotein Particle Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Positive Regulation Of Protein Import Cellular Response To Interleukin-12 Positive Regulation Of Proteolysis Membrane Raft Negative Regulation Of Receptor Catabolic Process Positive Regulation Of Intracellular Cholesterol Transport PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Leukocyte Migration Endosome To Plasma Membrane Transport Vesicle
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