MEX3C

Description		mex-3 RNA binding family member C
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GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Chondrocyte Hypertrophy Regulation Of Fat Cell Differentiation Energy Homeostasis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Atrial fibrillation ( 29892015 30061737) Femur bone mineral density x serum urate levels interaction ( 34046847) Immune response to anthrax vaccine ( 22658931) Immune response to smallpox vaccine (IL-6) ( 22610502) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Systolic blood pressure ( 30224653 30578418) Weight ( 34074324)
Novel Interacting Genes		7 novel interacting genes: LINC00839 PTEN RAB27B SOCS3 UBE2D2 UBE2D3 UBE2L3
Interacting Genes		7 interacting genes: LINC00839 PTEN RAB27B SOCS3 UBE2D2 UBE2D3 UBE2L3
Entrez ID		51320
HPRD ID		15255
Ensembl ID		ENSG00000176624
Uniprot IDs		Q5U5Q3
PDB IDs		5WWW 5WWX 5WWZ 5ZI6
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Modification Process Protein Polyubiquitination Ubiquitin-protein Transferase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Protein Targeting To Mitochondrion Post-translational Protein Modification Protein Autoubiquitination Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Cytoplasmic Side Of Plasma Membrane Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Protein K48-linked Ubiquitination Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Proteolysis Involved In Protein Catabolic Process Protein Metabolic Process Regulation Of Synaptic Vesicle Clustering Platelet Dense Granule Membrane Negative Regulation Of Peptidyl-serine Phosphorylation Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Anaphase-promoting Complex Binding Postsynaptic Density Assembly Forebrain Morphogenesis Presynaptic Membrane Assembly Nucleotide Binding Anterograde Axonal Protein Transport Ubiquitin-protein Transferase Activator Activity Cellular Response To Interleukin-17 Protein Tyrosine Kinase Inhibitor Activity Presynaptic Membrane Organization Branching Involved In Labyrinthine Layer Morphogenesis Postsynaptic Specialization Assembly Schmidt-Lanterman Incisure Negative Regulation Of Excitatory Postsynaptic Potential Locomotor Rhythm Cellular Response To Electrical Stimulus
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