FAM13B

Description		family with sequence similarity 13 member B
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	GTPase Activator Activity
	Biological Process	Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 29892015 30061737) Autism spectrum disorder or schizophrenia ( 28540026) Plateletcrit ( 32888494)
Novel Interacting Genes		9 novel interacting genes: AGTR1 CDC42 KDM3B LINC00839 RAC1 SAMHD1 YWHAE YWHAG YWHAZ
Interacting Genes		9 interacting genes: AGTR1 CDC42 KDM3B LINC00839 RAC1 SAMHD1 YWHAE YWHAG YWHAZ
Entrez ID		51306
HPRD ID		06464
Ensembl ID		ENSG00000031003
Uniprot IDs		A0A2X0SG06 A0A8I5KSB9 Q9NYF5
PDB IDs
Enriched GO Terms of Interacting Partners?		Focal Adhesion Protein Sequestering Activity Phosphoserine Residue Binding G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Establishment Of Golgi Localization Thioesterase Binding Melanosome Golgi Localization Intracellular Signaling Cassette Angiotensin-activated Signaling Pathway GTP-dependent Protein Binding Intracellular Signal Transduction Positive Regulation Of Lamellipodium Assembly Phagocytosis, Engulfment Negative Regulation Of Immune System Process Positive Regulation Of Lamellipodium Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Protein Targeting Negative Regulation Of Immune Response Regulation Of Lamellipodium Assembly Protein Domain Specific Binding Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Substantia Nigra Development Membrane Invagination Regulation Of Cell Communication Small GTPase-mediated Signal Transduction Regulation Of Signaling Positive Regulation Of Stress Fiber Assembly Regulation Of Lamellipodium Organization Non-canonical Wnt Signaling Pathway Cellular Response To Glucose Starvation Angiotensin Type I Receptor Activity Neural Nucleus Development Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Synapse Organization Positive Regulation Of Actin Filament Bundle Assembly Negative Regulation Of TORC1 Signaling TORC1 Signaling DGTPase Activity DGTP Binding Triphosphoric Monoester Hydrolase Activity Deoxynucleoside Triphosphate Hydrolase Activity Regulation Of Defense Response G Protein Activity Regulation Of Immune System Process GTP Binding Cell Migration Bradykinin Receptor Binding Intracellular Protein Localization Cytoplasmic Ribonucleoprotein Granule
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