C1RL

Description		complement C1r subcomponent like
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome Blood Microparticle
	Molecular Function	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Immune System Process Proteolysis Complement Activation, Classical Pathway Zymogen Activation Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)
Novel Interacting Genes		2 novel interacting genes: HP SPP1
Interacting Genes		2 interacting genes: HP SPP1
Entrez ID		51279
HPRD ID		07093
Ensembl ID		ENSG00000139178
Uniprot IDs		F5GWF3 F5H7C8 Q6P672 Q9NZP8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Hemoglobin Binding Androgen Catabolic Process Negative Regulation Of Hydrogen Peroxide Metabolic Process Cellular Response To Testosterone Stimulus Haptoglobin-hemoglobin Complex Positive Regulation Of Bone Resorption Response To Macrophage Colony-stimulating Factor Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration Response To 2,3,7,8-tetrachlorodibenzodioxine Hormone Catabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Endocytic Vesicle Lumen Antioxidant Activity Regulation Of Collateral Sprouting Decidualization Small Molecule Binding Steroid Catabolic Process Androgen Metabolic Process Regulation Of Axon Regeneration Response To Vitamin D Regulation Of Neuron Projection Regeneration Extracellular Matrix Binding Zymogen Activation Negative Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Bone Resorption Acute-phase Response Response To Testosterone Embryo Implantation Regulation Of Bone Remodeling Tertiary Granule Lumen Negative Regulation Of Axonogenesis Specific Granule Lumen Acute Inflammatory Response Extracellular Space Response To Vitamin Cellular Oxidant Detoxification Regulation Of Tissue Remodeling Positive Regulation Of Lipid Transport Response To Hydrogen Peroxide Negative Regulation Of Developmental Growth Biomineral Tissue Development Cellular Detoxification Extracellular Region Extracellular Exosome
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