PHF20

Description		PHD finger protein 20
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Nuclear Membrane NSL Complex MLL1 Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription
Pathways		HATs acetylate histones Regulation of TP53 Degradation Regulation of TP53 Activity through Association with Co-factors Stabilization of p53 Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Height ( 25282103 28552196) Hip circumference adjusted for BMI ( 34021172) Mean platelet volume ( 32888494) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		4 novel interacting genes: CEP250 H3C1 H4C1 LIG1
Interacting Genes		4 interacting genes: CEP250 H3C1 H4C1 LIG1
Entrez ID		51230
HPRD ID		08514
Ensembl ID		ENSG00000025293
Uniprot IDs		Q9BVI0
PDB IDs		2LDM 3P8D 3Q1J 3QII 3SD4 5TAB 5TBN
Enriched GO Terms of Interacting Partners?		Okazaki Fragment Processing Involved In Mitotic DNA Replication Nucleosome Telomere Organization Nucleosome Assembly Protein-containing Complex Nucleosome Organization Structural Constituent Of Chromatin DNA Ligase (ATP) Activity Lagging Strand Elongation DNA Replication, Okazaki Fragment Processing DNA Ligase Activity Protein-DNA Complex Assembly Regulation Of Centriole-centriole Cohesion Positive Regulation Of Protein Localization To Centrosome Protein Heterodimerization Activity Chromosome Organization DNA Strand Elongation Involved In DNA Replication Base-excision Repair, Gap-filling Centriole-centriole Cohesion Regulation Of Protein Localization To Centrosome Spindle Pole Centrosome V(D)J Recombination DNA Strand Elongation CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Detection Of Light Stimulus Involved In Visual Perception Extracellular Exosome Protein Localization To Centrosome Mismatch Repair DNA Binding Protein Localization To Organelle Base-excision Repair Chromatin Remodeling Regulation Of Megakaryocyte Differentiation Chromosome Protein Localization To Chromosome, Centromeric Region Cellular Component Assembly Somatic Cell DNA Recombination Organelle Organization Protein Localization To Cytoskeleton Protein Localization To Chromatin Non-motile Cilium Assembly Chromatin Organization Photoreceptor Inner Segment Detection Of Light Stimulus Photoreceptor Outer Segment
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