TFB1M

Description		transcription factor B1, mitochondrial
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	RRNA (adenine-N6,N6-)-dimethyltransferase Activity DNA Binding RNA Binding Protein Binding Methyltransferase Activity Transferase Activity Mitochondrial Transcription Factor Activity S-adenosyl-L-methionine Binding
	Biological Process	RRNA Modification RRNA Processing Transcription Initiation At Mitochondrial Promoter RRNA Methylation Methylation
Pathways		Transcriptional activation of mitochondrial biogenesis rRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Dimensional psychopathology (Arousal) ( 29496196) Dimensional psychopathology (Negative) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Metabolite levels ( 23823483) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Novel Interacting Genes		3 novel interacting genes: POLRMT TFAM VEGFB
Interacting Genes		3 interacting genes: POLRMT TFAM VEGFB
Entrez ID		51106
HPRD ID		09515
Ensembl ID		ENSG00000029639
Uniprot IDs		E5KTM5 Q8WVM0
PDB IDs		6AAX 6AJK 8CSP 8CSQ 8CSR 8CSU
Enriched GO Terms of Interacting Partners?		Mitochondrial Promoter Sequence-specific DNA Binding Transcription Initiation At Mitochondrial Promoter Mitochondrial Transcription Mitochondrial Nucleoid Mitochondrial RNA Metabolic Process DNA-templated Transcription Initiation Mitochondrial DNA-directed RNA Polymerase Complex Macromolecule Biosynthetic Process Mitochondrial Transcription Factor Activity Vascular Endothelial Growth Factor Receptor 1 Binding Vascular Endothelial Growth Factor Receptor Binding Response To Decreased Oxygen Levels Response To Hypoxia Positive Regulation Of Vascular Wound Healing Positive Regulation Of Mast Cell Chemotaxis Response To Oxygen Levels 5'-3' RNA Polymerase Activity Regulation Of Mast Cell Chemotaxis Mitochondrial Matrix DNA-templated Transcription Mitochondrial DNA Replication Sequence-specific DNA Binding Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Vascular Wound Healing Induction Of Positive Chemotaxis Positive Regulation Of Vascular Permeability Mitochondrial DNA Metabolic Process Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Positive Chemotaxis Coronary Vasculature Development DNA-directed RNA Polymerase Activity 3'-5'-RNA Exonuclease Activity Protein-containing Complex Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Chemoattractant Activity DNA-directed RNA Polymerase Complex Sprouting Angiogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Nucleobase-containing Compound Biosynthetic Process Cardiac Muscle Contraction Positive Chemotaxis Regulation Of Vascular Permeability DNA-templated DNA Replication Transcription Coactivator Binding Positive Regulation Of Peptidyl-tyrosine Phosphorylation Heat Shock Protein Binding Positive Regulation Of Wound Healing Platelet Alpha Granule Lumen
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