UTP18

Description		UTP18 small subunit processome component
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane Small-subunit Processome Pwp2p-containing Subcomplex Of 90S Preribosome
	Molecular Function	RNA Binding Protein Binding
	Biological Process	RRNA Processing Ribosomal Small Subunit Biogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Hip circumference adjusted for BMI ( 34021172) Menarche (age at onset) ( 27182965) Metabolite levels ( 23823483)
Novel Interacting Genes		10 novel interacting genes: CSNK2A1 ERBB2 HDAC5 KCNJ2 MBTD1 OGT PRDM1 RSAD1 TLR8 TXK
Interacting Genes		10 interacting genes: CSNK2A1 ERBB2 HDAC5 KCNJ2 MBTD1 OGT PRDM1 RSAD1 TLR8 TXK
Entrez ID		51096
HPRD ID		10825
Ensembl ID		ENSG00000011260
Uniprot IDs		Q9Y5J1
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Sebum Secreting Cell Proliferation Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Response To Stress Adaptive Immune Response Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Sin3-type Complex Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Protein Catabolic Process Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Cellular Response To Mechanical Stimulus Positive Regulation Of Type II Interferon Production Negative Regulation Of Nucleobase-containing Compound Metabolic Process Neuron Differentiation Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Extrathymic T Cell Differentiation Protein Localization To Vacuole Positive Regulation Of Signal Transduction ERBB3:ERBB2 Complex Relaxation Of Skeletal Muscle Coproporphyrinogen Oxidase Activity Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Translation Transferase Activity Regulation Of Translational Initiation Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body RNA Polymerase I Core Binding Protein O-acetylglucosaminyltransferase Activity Toll-like Receptor 8 Signaling Pathway Identical Protein Binding
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