FAM135B

Description		family with sequence similarity 135 member B
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding
	Biological Process	Lipid Metabolic Process
Pathways
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Cognitive performance ( 20125193) Disease progression in age-related macular degeneration ( 29346644) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Inflammatory biomarkers ( 22228203) Metabolite levels ( 23823483) Neuritic plaque ( 31497858) Periodontitis (PAL4Q3) ( 24024966) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
Novel Interacting Genes		1 novel interacting genes: KAT5
Interacting Genes		1 interacting genes: KAT5
Entrez ID		51059
HPRD ID		14230
Ensembl ID		ENSG00000147724
Uniprot IDs		Q49AJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H2AK5 Acetyltransferase Activity Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Histone H2A Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Phosphatidylethanolamine Biosynthetic Process Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Piccolo Histone Acetyltransferase Complex Positive Regulation Of Mitotic Sister Chromatid Segregation Regulation Of Metaphase Plate Congression Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Positive Regulation Of Triglyceride Biosynthetic Process Histone H4K16 Acetyltransferase Activity Aggrephagy Peptidyl-lysine Acetylation Lipid Droplet Disassembly Protein Targeting To Vacuole Involved In Autophagy Positive Regulation Of Protein Acetylation Positive Regulation Of Aggrephagy Swr1 Complex Histone H4 Acetyltransferase Activity CGAS/STING Signaling Pathway DNA Double-strand Break Processing DNA Repair-dependent Chromatin Remodeling Negative Regulation Of Myoblast Differentiation Negative Regulation Of Interleukin-2 Production Positive Regulation Of Circadian Rhythm Regulation Of Attachment Of Spindle Microtubules To Kinetochore Histone Acetyltransferase Complex Positive Regulation Of Regulatory T Cell Differentiation NuA4 Histone Acetyltransferase Complex Triglyceride Biosynthetic Process Sperm DNA Condensation Protein-lysine-acetyltransferase Activity Phosphatidylcholine Biosynthetic Process Regulation Of Hematopoietic Stem Cell Differentiation Attachment Of Mitotic Spindle Microtubules To Kinetochore Acetyltransferase Activity Positive Regulation Of Triglyceride Metabolic Process Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Phosphatidylethanolamine Metabolic Process Protein Localization To Site Of Double-strand Break Positive Regulation Of Chromosome Segregation Histone Acetyltransferase Activity Protein Acetylation Establishment Of Mitotic Spindle Localization Nuclear Lumen
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