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CLEC4A
Description
C-type lectin domain family 4 member A
Image
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Calcium Ion Binding
D-mannose Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
Metal Ion Binding
Biological Process
Negative Regulation Of Cytokine Production
Adaptive Immune Response
Immune System Process
Plasmacytoid Dendritic Cell Antigen Processing And Presentation
Cell Adhesion
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Tumor Necrosis Factor Production
CD8-positive, Alpha-beta T Cell Activation
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Innate Immune Response
Antifungal Innate Immune Response
Pathways
Dectin-2 family
Drugs
Diseases
GWAS
Novel Interacting Genes
3 novel interacting genes:
KAT8
LMNA
PTPN6
Interacting Genes
3 interacting genes:
KAT8
LMNA
PTPN6
Entrez ID
50856
HPRD ID
05604
Ensembl ID
ENSG00000111729
Uniprot IDs
Q9UMR7
PDB IDs
5B1W
5B1X
Enriched GO Terms of Interacting Partners
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Nuclear Lumen
DNA Double-strand Break Attachment To Nuclear Envelope
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Gene Expression
Nuclear Matrix
Cell Development
Heterochromatin Formation
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Gene Expression
Structural Constituent Of Nuclear Lamina
Hemopoiesis
Epididymis Development
Positive Regulation Of Skeletal Muscle Satellite Cell Differentiation
Protein Propionyltransferase Activity
Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity
Lamin Filament
Nuclear Pore Localization
Epigenetic Regulation Of Gene Expression
CD27 Signaling Pathway
Myeloid Cell Differentiation
Negative Regulation Of Mast Cell Activation Involved In Immune Response
MSL Complex
Post-embryonic Hemopoiesis
Negative Regulation Of Macromolecule Biosynthetic Process
Ventricular Cardiac Muscle Cell Development
Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Mesenchymal Cell Proliferation
Non-membrane Spanning Protein Tyrosine Phosphatase Activity
Negative Regulation Of Neutrophil Activation
Phosphorylation-dependent Protein Binding
Negative Regulation Of Mast Cell Activation
Inflammatory Response To Wounding
Regulation Of Neutrophil Activation
Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Alpha-beta T Cell Receptor Complex
Neutrophil Activation Involved In Immune Response
Negative Regulation Of Cytokine Production
Negative Regulation Of Inflammatory Response To Wounding
Negative Regulation Of B Cell Receptor Signaling Pathway
NSL Complex
Skeletal Muscle Satellite Cell Differentiation
Histone H4K8 Acetyltransferase Activity
Histone H4K16 Acetyltransferase Activity
Histone H4K5 Acetyltransferase Activity
Positive Regulation Of Skeletal Muscle Cell Differentiation
Regulation Of Mitochondrial Transcription
Histone H4 Acetyltransferase Activity
Nuclear Lamina
Negative Regulation Of Biosynthetic Process
Regulation Of Inflammatory Response To Wounding
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