COL5A3

Description		collagen type V alpha 3 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type V Trimer Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Collagen Binding Heparin Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Proteoglycan Binding
	Biological Process	Cell-matrix Adhesion Collagen Fibril Organization Skin Development
Pathways		Collagen degradation Fibronectin matrix formation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Syndecan interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions MET activates PTK2 signaling Collagen chain trimerization Attachment of bacteria to epithelial cells Developmental Lineage of Pancreatic Ductal Cells
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: COL1A2 COL5A1
Interacting Genes		2 interacting genes: COL1A2 COL5A1
Entrez ID		50509
HPRD ID		00369
Ensembl ID		ENSG00000080573
Uniprot IDs		P25940
PDB IDs
Enriched GO Terms of Interacting Partners?		Fibrillar Collagen Trimer Platelet-derived Growth Factor Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen Metabolic Process Collagen Fibril Organization Collagen Trimer Extracellular Matrix Structural Constituent Blood Vessel Development Protein Heterotrimerization Integrin Biosynthetic Process Extracellular Structure Organization Extracellular Matrix Organization Collagen Type I Trimer Endoplasmic Reticulum Lumen Collagen Type V Trimer Negative Regulation Of Endodermal Cell Differentiation Tendon Development Extracellular Matrix Collagen Type XI Trimer Animal Organ Morphogenesis Skin Morphogenesis Collagen Biosynthetic Process Proteoglycan Binding Tissue Development Wound Healing, Spreading Of Epidermal Cells Protein Trimerization Protein Heterooligomerization Extracellular Matrix Assembly Wound Healing, Spreading Of Cells SMAD Binding Skin Development Bone Mineralization Animal Organ Development Heart Morphogenesis Anatomical Structure Morphogenesis Eye Morphogenesis Rho Protein Signal Transduction Connective Tissue Development Sensory Organ Morphogenesis Cellular Response To Amino Acid Stimulus Biomineral Tissue Development Basement Membrane Odontogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Protease Binding Response To Amino Acid Extracellular Region Integrin Binding Heparin Binding Regulation Of Blood Pressure
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