ATP2B2

Description		ATPase plasma membrane Ca2+ transporting 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Dendritic Spine Membrane Intracellular Membrane-bounded Organelle Synapse Extracellular Exosome Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Nucleotide Binding P-type Calcium Transporter Activity Calcium Ion Binding Protein Binding Calmodulin Binding ATP Binding ATP Hydrolysis Activity PDZ Domain Binding Metal Ion Binding P-type Calcium Transporter Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Sensory Perception Of Sound Neuron Differentiation Monoatomic Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Regulation Of Cardiac Conduction
Pathways		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases
Drugs		Ritodrine Halothane Desflurane Sevoflurane
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Cognitive decline rate in late mild cognitive impairment ( 26252872) Femur bone mineral density x serum urate levels interaction ( 34046847) Hip circumference adjusted for BMI ( 34021172) Manganese levels ( 26025379) Metabolite levels ( 19043545)
Novel Interacting Genes		8 novel interacting genes: DLG1 DLG2 DLG4 ERBIN NHERF2 PDZD11 PRKCA SNTA1
Interacting Genes		8 interacting genes: DLG1 DLG2 DLG4 ERBIN NHERF2 PDZD11 PRKCA SNTA1
Entrez ID		491
HPRD ID		00160
Ensembl ID		ENSG00000157087
Uniprot IDs		A0A2U3U055 Q01814
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuromuscular Junction Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Ionotropic Glutamate Receptor Binding Establishment Or Maintenance Of Cell Polarity Adherens Junction Receptor Localization To Synapse Receptor Clustering Protein Localization To Synapse Basolateral Plasma Membrane GMP Kinase Activity Protein Localization To Cell Junction Protein Localization To Membrane GDP Metabolic Process Kinase Binding Postsynaptic Density Membrane Juxtaparanode Region Of Axon Cell Adhesion Cellular Response To Potassium Ion Anchoring Junction Plasma Membrane Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Response To Potassium Ion Localization Within Membrane Regulation Of System Process GMP Metabolic Process Cell Junction Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Protein Localization To Cell Periphery Regulation Of Sodium Ion Transmembrane Transport Postsynaptic Density Regulation Of Biological Quality Phosphatase Binding Chemical Synaptic Transmission Synaptic Membrane Lateral Plasma Membrane Neuron Projection Trans-synaptic Signaling Synaptic Signaling Protein-containing Complex Localization Regulation Of Sodium Ion Transport P2Y1 Nucleotide Receptor Binding Intracellular Protein Localization Nucleoside Monophosphate Metabolic Process Ribonucleoside Diphosphate Metabolic Process Voltage-gated Potassium Channel Complex Nucleoside Diphosphate Metabolic Process Membrane
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