NNMT

Description		nicotinamide N-methyltransferase
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Nicotinamide N-methyltransferase Activity Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Transferase Activity Pyridine N-methyltransferase Activity
	Biological Process	Nicotinamide Metabolic Process Methylation NAD+ Biosynthetic Process Via The Salvage Pathway Positive Regulation Of Gluconeogenesis Positive Regulation Of Protein Deacetylation
Pathways		Methylation Nicotinate metabolism Metabolism of ingested SeMet, Sec, MeSec into H2Se
Drugs		Niacin
Diseases
GWAS		Asthma ( 29273806) Diisocyanate-induced asthma ( 25918132) Volumetric brain MRI ( 17903297)
Novel Interacting Genes		4 novel interacting genes: APP ATF6 BIRC5 BMF
Interacting Genes		4 interacting genes: APP ATF6 BIRC5 BMF
Entrez ID		4837
HPRD ID		02478
Ensembl ID		ENSG00000166741
Uniprot IDs		B0YJ53 P40261
PDB IDs		2IIP 3ROD 5YJF 6CHH 6ORR 6PVE 6PVS 7BKG 7BLE 7EGU 7EHZ 7EI2 7ET7 7EU5 7NBJ 7NBM 7NBQ 7RKK 7RKL 7SOK 7WMC 7WMT 9ATV
Enriched GO Terms of Interacting Partners?		Enzyme Binding Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Protein Heterodimerization Activity Positive Regulation Of Response To Endoplasmic Reticulum Stress Protein-folding Chaperone Binding Survivin Complex Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ATF6-mediated Unfolded Protein Response Peptidase Inhibitor Activity Positive Regulation Of Mitotic Cell Cycle Cell Death Apoptotic Process Nervous System Process Programmed Cell Death Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Exit From Mitosis Cobalt Ion Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of ATF6-mediated Unfolded Protein Response Positive Regulation Of Intracellular Signal Transduction Interphase Microtubule Organizing Center Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Chromosome Passenger Complex
Tagcloud ?