NEU2

Description		neuraminidase 2
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GO Annotations	Cellular Component	Cytoplasm Lysosome Cytosol Membrane Catalytic Complex
	Molecular Function	Exo-alpha-sialidase Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds
	Biological Process	Glycoprotein Catabolic Process Lipid Metabolic Process Ganglioside Catabolic Process Oligosaccharide Catabolic Process Lipid Catabolic Process Glycosphingolipid Catabolic Process
Pathways		Sialic acid metabolism Glycosphingolipid catabolism
Drugs		Oseltamivir Zanamivir 2-deoxy-2,3-dehydro-N-acetylneuraminic acid 5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID
Diseases
GWAS		Contrast sensitivity ( 24152035) High density lipoprotein cholesterol levels ( 31928498) Metabolic syndrome ( 31589552)
Novel Interacting Genes		2 novel interacting genes: CYSRT1 NOTCH2NLA
Interacting Genes		2 interacting genes: CYSRT1 NOTCH2NLA
Entrez ID		4759
HPRD ID		05702
Ensembl ID		ENSG00000115488
Uniprot IDs		Q9Y3R4
PDB IDs		1SNT 1SO7 1VCU 2F0Z 2F10 2F11 2F12 2F13 2F24 2F25 2F26 2F27 2F28 2F29 4NC5 4NCS
Enriched GO Terms of Interacting Partners?		Biological Process Involved In Interaction With Symbiont Skin Epidermis Development Establishment Of Skin Barrier Positive Regulation Of Notch Signaling Pathway Notch Binding Cornified Envelope
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