NEK3

Description		NIMA related kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Axon Cell Projection
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Cell Division
Pathways
Drugs		Fostamatinib
Diseases
GWAS
Novel Interacting Genes		6 novel interacting genes: BPGM CDCA8 NMNAT1 PRLR VAV1 VAV2
Interacting Genes		6 interacting genes: BPGM CDCA8 NMNAT1 PRLR VAV1 VAV2
Entrez ID		4752
HPRD ID		04954
Ensembl ID		ENSG00000136098
Uniprot IDs		P51956 Q6ZN64
PDB IDs
Enriched GO Terms of Interacting Partners?		Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-epsilon Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Phosphotyrosine Residue Binding Fc Receptor Signaling Pathway Cellular Response To Xenobiotic Stimulus Platelet Activation Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Size Phosphoglycerate Mutase Activity Nicotinamide Nucleotide Metabolic Process Bisphosphoglycerate Mutase Activity Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Prolactin Receptor Activity Positive Regulation Of Signal Transduction Nicotinate-nucleotide Adenylyltransferase Activity Negative Regulation Of Apoptotic DNA Fragmentation Nicotinamide-nucleotide Adenylyltransferase Activity ATP Metabolic Process Prolactin Signaling Pathway Activation Of Janus Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling Protein ADP-ribosyltransferase-substrate Adaptor Activity ATP Generation From Poly-ADP-D-ribose Nicotinamide Metabolic Process Chromosome Passenger Complex Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Guanyl-nucleotide Exchange Factor Activity Purine Ribonucleotide Metabolic Process Intramolecular Phosphotransferase Activity Establishment Of Blood-brain Barrier Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Positive Regulation Of Immune System Process Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Mammary Gland Epithelium Development Prostate Gland Growth Response To Xenobiotic Stimulus Regulation Of Cellular Component Size Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Small GTPase-mediated Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Phosphorylation-dependent Protein Binding Positive Regulation Of Mitotic Cytokinesis
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