NEFM

Description		neurofilament medium chain
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Intermediate Filament Neurofilament Axon Cell Projection Intermediate Filament Cytoskeleton Neurofibrillary Tangle Postsynaptic Intermediate Filament Cytoskeleton
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Microtubule Binding
	Biological Process	Neurofilament Bundle Assembly
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Fear of minor pain ( 28701861) Idiopathic dilated cardiomyopathy ( 29495422) Interleukin-6 levels ( 22205395) Metabolite levels ( 23823483)
Novel Interacting Genes		12 novel interacting genes: APOE DISC1 DRD2 DSCAM FOS ITSN1 MINK1 NEFH RB1 SMAD2 STXBP1 TNIK
Interacting Genes		12 interacting genes: APOE DISC1 DRD2 DSCAM FOS ITSN1 MINK1 NEFH RB1 SMAD2 STXBP1 TNIK
Entrez ID		4741
HPRD ID		01205
Ensembl ID		ENSG00000104722
Uniprot IDs		P07197 Q9UK51
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Projection Organization Axon Intracellular Signal Transduction Intracellular Signaling Cassette Anatomical Structure Morphogenesis Positive Regulation Of Developmental Process Glutamatergic Synapse Cell Projection Morphogenesis Neuron Projection Morphogenesis Chemical Synaptic Transmission Trans-synaptic Signaling Synaptic Signaling Positive Regulation Of Cellular Component Organization Regulation Of Developmental Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Cell Communication Regulation Of Signaling Regulation Of Dendritic Spine Development Positive Regulation Of Cell Development Modulation Of Chemical Synaptic Transmission Developmental Process Positive Regulation Of Cell Differentiation Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Growth Hormone Secretion Regulation Of Axon Extension Cell-cell Signaling Regulation Of Growth Signal Transduction Regulation Of Growth Hormone Secretion Regulation Of Synapse Organization Positive Regulation Of Multicellular Organismal Process Signaling Regulation Of Developmental Growth Regulation Of Cellular Component Organization Cell Communication Intracellular Protein Localization Identical Protein Binding Memory Protein-containing Complex Binding Positive Regulation Of Cell Projection Organization Cell Population Proliferation Regulation Of Neurogenesis Regulation Of Postsynapse Organization Regulation Of Cell Growth Negative Regulation Of Epithelial Cell Proliferation Cell Surface Receptor Signaling Pathway SMAD Protein Signal Transduction Disordered Domain Specific Binding Regulation Of Cell Development
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