MYO1C

Description		myosin IC
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GO Annotations	Cellular Component	Stress Fiber Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Actin Filament Plasma Membrane Microvillus Brush Border Cell Cortex Basal Plasma Membrane Actin Cytoskeleton Membrane Lateral Plasma Membrane Myosin Complex Unconventional Myosin Complex Nuclear Body Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Filamentous Actin Stereocilium Ruffle Membrane Cell Projection Membrane Raft Phagocytic Vesicle Stereocilium Membrane Extracellular Exosome B-WICH Complex Plasma Membrane Bounded Cell Projection
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Signaling Receptor Binding Protein Binding Calmodulin Binding ATP Binding Small GTPase Binding Actin Filament Binding
	Biological Process	Chromatin Remodeling Protein Targeting To Membrane Endocytosis Actin Filament Organization Actin Filament-based Movement Vesicle Transport Along Actin Filament Positive Regulation Of Cell Migration Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Cellular Response To Type II Interferon Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cellular Response To Insulin Stimulus Regulation Of Bicellular Tight Junction Assembly
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737) Mean platelet volume ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30578418) White blood cell count ( 32888494)
Novel Interacting Genes		12 novel interacting genes: BAZ1B CBL CDC42 KHDRBS1 MYH10 NEIL3 PTEN RBFOX2 RBPMS RRN3 SEPTIN9 WEE2-AS1
Interacting Genes		12 interacting genes: BAZ1B CBL CDC42 KHDRBS1 MYH10 NEIL3 PTEN RBFOX2 RBPMS RRN3 SEPTIN9 WEE2-AS1
Entrez ID		4641
HPRD ID		09411
Ensembl ID		ENSG00000197879
Uniprot IDs		F5H6E2 O00159
PDB IDs		4BYF
Enriched GO Terms of Interacting Partners?		Regulation Of Alternative MRNA Splicing, Via Spliceosome Dendritic Spine Morphogenesis Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nucleus Localization Dendritic Spine Organization Nuclear Migration Molecular Function Inhibitor Activity Regulation Of RNA Splicing Protein Tyrosine Kinase Binding Neuron Projection Organization Postsynapse Organization Nucleic Acid Binding Establishment Of Organelle Localization Neuron Projection Morphogenesis Negative Regulation Of Synaptic Vesicle Clustering Histone H2AXY142 Kinase Activity Grb2-Sos Complex MRNA Binding MCM Complex Binding Cell Projection Morphogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction GBD Domain Binding Storage Vacuole Fourth Ventricle Development Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity WICH Complex Negative Regulation Of Mitotic Chromosome Condensation Regulation Of MRNA Metabolic Process Neuron Projection Stress Fiber Positive Regulation Of Transport Endothelin Receptor Signaling Pathway Involved In Heart Process Actin Cytoskeleton Organization Cytoskeleton-dependent Cytokinesis Myosin II Filament Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission RNA Polymerase I Core Binding SH3 Domain Binding Regulation Of Rap Protein Signal Transduction Actin Filament-based Process Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Cytoplasmic Side Of Plasma Membrane Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Chromosome Condensation
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