MUC5AC

Description		mucin 5AC, oligomeric mucus/gel-forming
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen Plasma Membrane Extracellular Matrix Extracellular Exosome Mucus Layer
	Molecular Function	Extracellular Matrix Structural Constituent Metal Ion Binding
	Biological Process
Pathways		Defective GALNT3 causes HFTC Defective C1GALT1C1 causes TNPS Defective GALNT12 causes CRCS1 Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Asthma ( 31959851 34103634) Asthma (adult onset) ( 31036433) Asthma (moderate or severe) ( 30552067) Idiopathic pulmonary fibrosis ( 24429156)
Novel Interacting Genes		2 novel interacting genes: GALNT12 GALNT14
Interacting Genes		2 interacting genes: GALNT12 GALNT14
Entrez ID		4586
HPRD ID
Ensembl ID		ENSG00000215182
Uniprot IDs		P98088
PDB IDs		5AJN 5AJO 5AJP 8OV0 8QSP 8QTB 8QTV 8R1U 8R1Z 8UI6 8UJF 8V9Q 9GVJ 9GVQ
Enriched GO Terms of Interacting Partners?		Polypeptide N-acetylgalactosaminyltransferase Activity Protein O-linked Glycosylation Via N-acetyl-galactosamine Protein O-linked Glycosylation Protein Glycosylation Glycosylation Macromolecule Glycosylation Carbohydrate Binding Glycosyltransferase Activity Glycoprotein Biosynthetic Process Glycoprotein Metabolic Process Carbohydrate Derivative Biosynthetic Process Golgi Membrane Carbohydrate Derivative Metabolic Process Golgi Apparatus Macromolecule Biosynthetic Process Protein Modification Process Transferase Activity Protein Metabolic Process
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