MT-ND4L

Description		NADH dehydrogenase subunit 4L
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity, Acting On NAD(P)H
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Mitochondrial translation termination
Drugs		NADH
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Novel Interacting Genes		2 novel interacting genes: GLP1R STAT1
Interacting Genes		2 interacting genes: GLP1R STAT1
Entrez ID		4539
HPRD ID		08955
Ensembl ID		ENSG00000212907
Uniprot IDs		P03901 Q7GXZ4
PDB IDs		5XTC 5XTD
Enriched GO Terms of Interacting Partners?		Cellular Response To Peptide Hormone Stimulus Response To Peptide Hormone Glucagon-like Peptide 1 Receptor Activity Glucagon Receptor Activity Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development ISGF3 Complex Negative Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Cellular Response To Hormone Stimulus Response To Psychosocial Stress Post-translational Protein Targeting To Membrane, Translocation Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Interleukin-7-mediated Signaling Pathway Interleukin-27-mediated Signaling Pathway Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Cell Proliferation Involved In Metanephros Development Metanephric Mesenchymal Cell Differentiation Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Mesenchymal Cell Differentiation Involved In Kidney Development Interleukin-9-mediated Signaling Pathway CCR5 Chemokine Receptor Binding Cell Proliferation Involved In Kidney Development Cellular Response To Glucagon Stimulus Response To Hormone Regulation Of Nephron Tubule Epithelial Cell Differentiation Activation Of Adenylate Cyclase Activity Type II Interferon-mediated Signaling Pathway Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Lyase Activity Positive Regulation Of Cyclase Activity Response To Glucagon Cellular Response To Oxygen-containing Compound RNA Polymerase II Core Promoter Sequence-specific DNA Binding Mesenchymal Cell Proliferation Cellular Response To Interferon-beta Positive Regulation Of Interferon-alpha Production Histone Acetyltransferase Binding Renal Tubule Development Ubiquitin-like Protein Ligase Binding Positive Regulation Of Mesenchymal Cell Proliferation Intracellular Protein Transmembrane Transport Positive Regulation Of Blood Pressure Protein Phosphatase 2A Binding Tumor Necrosis Factor Receptor Binding Cell Differentiation Involved In Kidney Development Positive Regulation Of Defense Response To Virus By Host Positive Regulation Of Erythrocyte Differentiation
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