MSH4

Description		mutS homolog 4
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Condensed Nuclear Chromosome Synaptonemal Complex Nucleus Chromosome Recombination Nodule
	Molecular Function	Nucleotide Binding DNA Binding Double-stranded DNA Binding Protein Binding ATP Binding Mismatched DNA Binding ATP-dependent DNA Damage Sensor Activity
	Biological Process	Ovarian Follicle Development Mismatch Repair Homologous Chromosome Pairing At Meiosis Reciprocal Meiotic Recombination Spermatogenesis Female Gamete Generation Meiotic Cell Cycle
Pathways		Meiotic recombination
Drugs
Diseases
GWAS		Attention function in attention deficit hyperactive disorder ( 26174813) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Serum metabolite levels ( 23093944)
Novel Interacting Genes		10 novel interacting genes: ACADM CFTR DMC1 EIF3F MLH1 MLH3 MSH5 RAD51 RPA1 VBP1
Interacting Genes		10 interacting genes: ACADM CFTR DMC1 EIF3F MLH1 MLH3 MSH5 RAD51 RPA1 VBP1
Entrez ID		4438
HPRD ID		03658
Ensembl ID		ENSG00000057468
Uniprot IDs		O15457
PDB IDs
Enriched GO Terms of Interacting Partners?		ATP-dependent DNA Damage Sensor Activity Condensed Nuclear Chromosome Meiosis I Cell Cycle Process Meiotic Nuclear Division Nuclear Division Reciprocal Meiotic Recombination Mismatch Repair Condensed Chromosome Meiotic Cell Cycle Homologous Recombination Meiosis I Male Germ Cell Nucleus Chromosome Organization Involved In Meiotic Cell Cycle Mismatched DNA Binding Lateral Element DNA Recombination DNA Repair Chiasma DNA Strand Exchange Activity Single-stranded DNA Binding Chromosome Organization DNA Metabolic Process DNA Damage Response Reproductive Process Male Meiotic Nuclear Division Mismatch Repair Complex DNA Strand Invasion DNA Recombinase Assembly Cellular Response To Stress Double-strand Break Repair Double-strand Break Repair Involved In Meiotic Recombination Site Of Double-strand Break Response To Stress ATP Binding Double-stranded DNA Binding Mitotic Recombination Double-strand Break Repair Via Homologous Recombination Recombinational Repair Synaptonemal Complex Cellular Component Assembly Homologous Chromosome Pairing At Meiosis Chromatin Binding Chromosome, Telomeric Region Telomere Maintenance Via Telomere Lengthening Nuclear Chromosome ATP-dependent Activity, Acting On DNA Oogenesis Nucleic Acid Metabolic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity
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