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MTHFD2L

Description methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like
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GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Mitochondrial Matrix
  • Membrane
Molecular Function
  • Catalytic Activity
  • Methenyltetrahydrofolate Cyclohydrolase Activity
  • Methylenetetrahydrofolate Dehydrogenase (NAD+) Activity
  • Methylenetetrahydrofolate Dehydrogenase (NADP+) Activity
  • Protein Binding
  • Oxidoreductase Activity
  • Hydrolase Activity
Biological Process
  • Purine Nucleotide Biosynthetic Process
  • One-carbon Metabolic Process
  • Amino Acid Biosynthetic Process
  • Methionine Biosynthetic Process
  • 10-formyltetrahydrofolate Metabolic Process
  • Tetrahydrofolate Interconversion
  • Folic Acid Metabolic Process
Pathways
  • Metabolism of folate and pterines
Drugs
Diseases
GWAS
  • Cholesterol, total ( 25961943)
  • Immune reponse to smallpox (secreted IL-1beta) ( 22610502)
  • LDL cholesterol ( 25961943)
  • Neutrophil count ( 29403010)
  • White blood cell count ( 29403010)
Novel Interacting Genes 1 novel interacting genes: NTAQ1
Interacting Genes 1 interacting genes: NTAQ1
Entrez ID 441024
HPRD ID 17608
Ensembl ID ENSG00000163738
Uniprot IDs Q9H903
PDB IDs 7QEI
Enriched GO Terms of Interacting Partners?
  • Protein-N-terminal Glutamine Amidohydrolase Activity
  • Protein-N-terminal Asparagine Amidohydrolase Activity
  • Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides
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© Madhavi K. Ganapathiraju 2012-2025