MMP17

Description		matrix metallopeptidase 17
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Extracellular Matrix Side Of Membrane
	Molecular Function	Metalloendopeptidase Activity Enzyme Activator Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Metalloaminopeptidase Activity
	Biological Process	Kidney Development Proteolysis Extracellular Matrix Organization Collagen Catabolic Process Drinking Behavior
Pathways		Activation of Matrix Metalloproteinases
Drugs		Marimastat
Diseases
GWAS		Body mass index ( 26426971) Migraine ( 22683712) Psychosis proneness (perceptual aberration scale) ( 28525603)
Novel Interacting Genes		5 novel interacting genes: HSP90B1 LRP1 MMP2 POLE TNF
Interacting Genes		5 interacting genes: HSP90B1 LRP1 MMP2 POLE TNF
Entrez ID		4326
HPRD ID		03793
Ensembl ID		ENSG00000198598
Uniprot IDs		Q9ULZ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Amyloid-beta Regulation Of Amyloid-beta Clearance Astrocyte Activation Vascular Process In Circulatory System Circulatory System Process Cellular Response To Oxygen-containing Compound Response To Hypoxia Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Response To Nicotine Response To Oxygen Levels Response To Decreased Oxygen Levels Cellular Response To Amyloid-beta Positive Regulation Of Transcytosis Positive Regulation Of Protein Localization To Cell Periphery Alpha-2 Macroglobulin Receptor Activity Positive Regulation Of Protein Localization To Membrane Apolipoprotein Receptor Activity Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Cellular Response To Amino Acid Stimulus Response To Activity Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Response To Gram-negative Bacterium Negative Regulation Of Branching Involved In Lung Morphogenesis Cellular Response To Stress Response To Retinoic Acid Positive Regulation Of Reverse Cholesterol Transport Regulation Of Protein Localization To Plasma Membrane Regulation Of Transcytosis Response To Amino Acid Regeneration Chronic Inflammatory Response To Antigenic Stimulus Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Fractalkine Production Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Positive Regulation Of Vitamin D Biosynthetic Process Actin Rod Assembly Regulation Of Protein Localization To Cell Periphery Cell Activation Involved In Immune Response Lipoprotein Particle Receptor Binding Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Apoptotic Signaling Pathway Blood Vessel Diameter Maintenance Regulation Of Tube Size
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