Wiki-MPM

  • About
  • Browse
  • People
  • Funding
  • Updates

MMP11

Description matrix metallopeptidase 11
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Golgi Lumen
  • Extracellular Matrix
Molecular Function
  • Metalloendopeptidase Activity
  • Serine-type Endopeptidase Activity
  • Peptidase Activity
  • Metallopeptidase Activity
  • Zinc Ion Binding
  • Hydrolase Activity
  • Metal Ion Binding
Biological Process
  • Proteolysis
  • Extracellular Matrix Disassembly
  • Extracellular Matrix Organization
  • Collagen Fibril Organization
  • Collagen Catabolic Process
  • Negative Regulation Of Fat Cell Differentiation
  • Basement Membrane Organization
Pathways
  • Collagen degradation
  • Degradation of the extracellular matrix
  • Activation of Matrix Metalloproteinases
Drugs
  • Marimastat
  • Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide
Diseases
GWAS
  • Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597)
Novel Interacting Genes 2 novel interacting genes: PRPF40A SERPINA1
Interacting Genes 2 interacting genes: PRPF40A SERPINA1
Entrez ID 4320
HPRD ID 01705
Ensembl ID ENSG00000099953
Uniprot IDs B3KQS8 P24347
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025