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MICB
Description
MHC class I polypeptide-related sequence B
Image
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Membrane
Molecular Function
Natural Killer Cell Lectin-like Receptor Binding
Biological Process
Adaptive Immune Response
Immune System Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response
Response To Oxidative Stress
Response To Heat
Negative Regulation Of Defense Response
Killing Of Cells Of Another Organism
Response To Retinoic Acid
Gamma-delta T Cell Activation
Negative Regulation Of Defense Response To Virus By Host
Regulation Of Immune Response
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS
A body shape index (
34021172
)
AIDS progression (
19115949
)
Alcohol use disorder (
30940813
)
Allergic sensitization (
23817571
)
Apolipoprotein B levels (
32203549
)
Arterial stiffness index (
31235810
)
Asthma (
29273806
31619474
)
Asthma (childhood onset) (
29273806
31619474
)
Asthma and major depressive disorder (
31619474
)
Atopic dermatitis (
26482879
)
Autism spectrum disorder or schizophrenia (
28540026
)
Behcet's disease (
23001997
)
Cervical cancer (
28806749
)
Cold sores (
28928442
)
Coronary artery disease (
33020668
)
Crohn's disease (
23128233
)
Cutaneous lupus erythematosus (
25827949
)
Dengue shock syndrome (
22001756
)
Fasting insulin (
34059833
)
Handedness (non-right-handed vs right-handed) (
31504236
)
Hip circumference adjusted for BMI (
34021172
)
Hodgkin's lymphoma (
22286212
)
Inflammatory bowel disease (
28067908
)
Kawasaki disease (
33692975
)
Malaria (
31844061
)
Metabolic syndrome (
22399527
)
Midgestational circulating levels of PBDEs (
28235828
)
Monocyte count (
32888494
27863252
)
Mononucleosis (
28928442
)
Myositis (
26291516
)
Oral cavity cancer (
27749845
)
Parental longevity (combined parental attained age, Martingale residuals) (
29227965
)
Parental longevity (father's attained age) (
29227965
)
Platelet count (
32888494
)
Plateletcrit (
27863252
32888494
)
Pneumonia (
28928442
)
Psychosis (atypical) (
24132900
)
Pulmonary function (
21946350
)
Refractive error (
32231278
)
Rosacea symptom severity (
29771307
)
Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) (
26651848
)
Serum metabolite levels (
31636271
)
Serum metabolite levels (CMS) (
31636271
)
Triglyceride levels (
32203549
)
Ulcerative colitis (
28067908
)
Waist circumference adjusted for body mass index (
34021172
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
White matter hyperintensity volume (
33293549
)
White matter hyperintensity volume (adjusted for hypertension) (
33293549
)
Novel Interacting Genes
2 novel interacting genes:
KLRC4
KLRK1
Interacting Genes
2 interacting genes:
KLRC4
KLRK1
Entrez ID
4277
HPRD ID
03894
Ensembl ID
ENSG00000204516
Uniprot IDs
A0A0G2JHB5
A0A7D9H7X8
B4DUT9
B7Z8M1
F5H7Q8
Q29980
PDB IDs
1JE6
2WY3
Enriched GO Terms of Interacting Partners
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Stimulatory C-type Lectin Receptor Signaling Pathway
Cellular Response To Lectin
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Natural Killer Cell Mediated Immunity
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Natural Killer Cell Mediated Immunity
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Positive Regulation Of Cell Killing
Regulation Of Leukocyte Mediated Cytotoxicity
Positive Regulation Of Lymphocyte Mediated Immunity
Innate Immune Response-activating Signaling Pathway
Regulation Of Lymphocyte Mediated Immunity
Activation Of Innate Immune Response
Immune Response-activating Cell Surface Receptor Signaling Pathway
Negative Regulation Of Natural Killer Cell Chemotaxis
Positive Regulation Of Immune Effector Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Innate Immune Response
Negative Regulation Of Lymphocyte Chemotaxis
Immune Response-activating Signaling Pathway
External Side Of Plasma Membrane
Immune Response-regulating Signaling Pathway
Activation Of Immune Response
Positive Regulation Of Defense Response
Regulation Of Innate Immune Response
MHC Class Ib Receptor Activity
Positive Regulation Of Immune Response
Negative Regulation Of Lymphocyte Migration
Negative Regulation Of GTPase Activity
MHC Class I Protein Binding
Regulation Of Defense Response
Nitric Oxide Biosynthetic Process
Negative Regulation Of Leukocyte Chemotaxis
Regulation Of Lymphocyte Chemotaxis
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Nitric Oxide Metabolic Process
Reactive Nitrogen Species Metabolic Process
Negative Regulation Of Mononuclear Cell Migration
Negative Regulation Of Hydrolase Activity
Positive Regulation Of Nitric Oxide Biosynthetic Process
Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Nitric Oxide Metabolic Process
Natural Killer Cell Mediated Immunity
T Cell Costimulation
Negative Regulation Of Chemotaxis
Negative Regulation Of Leukocyte Migration
Natural Killer Cell Activation
Regulation Of Nitric Oxide Biosynthetic Process
Tagcloud
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