MEP1B

Description		meprin A subunit beta
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Meprin A Complex
	Molecular Function	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Proteolysis Inflammatory Response
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) TRAIL levels ( 27989323)
Novel Interacting Genes		13 novel interacting genes: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT TSPAN8
Interacting Genes		13 interacting genes: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT TSPAN8
Entrez ID		4225
HPRD ID		02667
Ensembl ID		ENSG00000141434
Uniprot IDs		J3QKX5 Q16820
PDB IDs		4GWM 4GWN 7AQ1 7AUW
Enriched GO Terms of Interacting Partners?		Hormone Activity Neuropeptide Hormone Activity G Protein-coupled Receptor Signaling Pathway Extracellular Space Feeding Behavior Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Neuropeptide Y Receptor Binding Extracellular Region Positive Regulation Of Hormone Secretion Signaling Receptor Binding Signal Transduction Regulation Of Peptide Hormone Secretion Regulation Of Biological Quality G Protein-coupled Receptor Binding Regulation Of Hormone Levels Cellular Response To Glucagon Stimulus Intestinal Epithelial Cell Differentiation Regulation Of Hormone Secretion Regulation Of Secretion By Cell Regulation Of Body Fluid Levels Regulation Of Transport Positive Regulation Of Secretion By Cell Neuropeptide Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Secretion Positive Regulation Of Secretion Response To Glucagon Receptor Ligand Activity Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Gluconeogenesis Regulation Of Appetite Positive Regulation Of Lipid Metabolic Process Regulation Of Intracellular Protein Transport Positive Regulation Of Lipid Catabolic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Behavior Positive Regulation Of Transport Regulation Of Protein Transport Cellular Response To Peptide Hormone Stimulus Peptidyl-serine Phosphorylation Regulation Of Cellular Localization Regulation Of Establishment Of Protein Localization Positive Regulation Of Glucose Metabolic Process Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Gluconeogenesis Short-day Photoperiodism Negative Regulation Of Coagulation
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