PIM3

Description		Pim-3 proto-oncogene, serine/threonine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Apoptotic Process Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Response To Forskolin
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Acne (severe) ( 24927181) Apolipoprotein A1 levels ( 32203549) Birth weight ( 31043758) Cannabis dependence ( 21668797) Type 2 diabetes ( 29632382 30297969 32499647) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 21297633 28067908)
Novel Interacting Genes		1 novel interacting genes: BAD
Interacting Genes		1 interacting genes: BAD
Entrez ID		415116
HPRD ID		15137
Ensembl ID		ENSG00000198355
Uniprot IDs		Q86V86
PDB IDs
Enriched GO Terms of Interacting Partners?		BAD-BCL-2 Complex Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Positive Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Mitochondrial Membrane Potential Regulation Of Type B Pancreatic Cell Development Cellular Response To Nicotine Positive Regulation Of Membrane Potential Cysteine-type Endopeptidase Activator Activity Regulation Of Cellular Response To Osmotic Stress Type B Pancreatic Cell Proliferation Regulation Of Response To Osmotic Stress Positive Regulation Of B Cell Differentiation Pore Complex Assembly Release Of Cytochrome C From Mitochondria Positive Regulation Of Release Of Cytochrome C From Mitochondria Glucose Catabolic Process Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of B Cell Differentiation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Release Of Cytochrome C From Mitochondria Response To Nicotine Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Epithelial Cell Differentiation ADP Metabolic Process Regulation Of Mitochondrial Membrane Permeability Apoptotic Mitochondrial Changes Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Membrane Permeability Regulation Of Mitochondrial Membrane Potential Cellular Response To Mechanical Stimulus Ribonucleoside Diphosphate Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Insulin Secretion Positive Regulation Of B Cell Activation Nucleoside Diphosphate Metabolic Process Protein Phosphatase Binding Regulation Of Mitochondrion Organization Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Carbohydrate Catabolic Process Mitochondrial Membrane Organization Extrinsic Apoptotic Signaling Pathway Phospholipid Binding Positive Regulation Of T Cell Differentiation Glucose Metabolic Process Positive Regulation Of Proteolysis Response To Mechanical Stimulus Epithelial Cell Proliferation Carbohydrate Homeostasis
Tagcloud ?