LSP1

Description		lymphocyte specific protein 1
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GO Annotations	Cellular Component	Plasma Membrane Actin Cytoskeleton Membrane Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding
	Biological Process	Chemotaxis Defense Response Cellular Defense Response Signal Transduction Cellular Response To Interleukin-7
Pathways
Drugs
Diseases
GWAS		Bladder cancer ( 24163127) Breast cancer ( 20453838 17529967 23535729 29059683 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Celiac disease ( 23936387) Central corneal thickness ( 32528159) Diastolic blood pressure ( 30487518 27618452 27841878) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Granulocyte percentage of myeloid white cells ( 27863252) Hypertension ( 30487518) Inflammatory bowel disease ( 28067908 23128233) Lymphocyte count ( 32888494) Mammographic density (dense area) ( 25342443) Mean arterial pressure ( 29403010 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (antihypertensives) ( 31015401) Medication use (beta blocking agents) ( 31015401) Methadone dose in opioid dependence ( 28115739) Milk allergy ( 25710614) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Potassium levels ( 29403010) Pulse pressure ( 30578418 27841878) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure ( 27618452 29403010 30487518 30578418 27841878) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Ulcerative colitis ( 28067908 21297633)
Novel Interacting Genes		11 novel interacting genes: ACTG1 BMPR2 CFTR GREB1 IL24 KLK6 LYPD3 MAPKAPK2 SCGB2A2 SNAI1 THRSP
Interacting Genes		11 interacting genes: ACTG1 BMPR2 CFTR GREB1 IL24 KLK6 LYPD3 MAPKAPK2 SCGB2A2 SNAI1 THRSP
Entrez ID		4046
HPRD ID		01083
Ensembl ID		ENSG00000130592
Uniprot IDs		A8K7L8 P33241
PDB IDs		3BH8 4NO0 4NO2
Enriched GO Terms of Interacting Partners?
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