LPP

Description		LIM domain containing preferred translocation partner in lipoma
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Anchoring Junction
	Molecular Function	Protein Binding Metal Ion Binding
	Biological Process	Cell Adhesion Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Addison's disease ( 33574239) Adult body size ( 32376654) Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184 31361310) Allergic sensitization ( 23817571 30013184) Allergy ( 27182965) Alopecia areata ( 25608926) Asthma ( 27182965 30929738 31361310 31619474 31959851 32296059 34103634) Asthma (childhood onset) ( 30929738 31036433) Asthma onset (childhood vs adult) ( 30929738) Autoimmune thyroid disease ( 32581359) Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) ( 22922229) B cell non-Hodgkin lymphoma ( 23749188) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Basal cell carcinoma ( 27539887 31174203 33549134) Celiac disease ( 18311140 20190752 22057235 30572963) Chronic kidney disease ( 29124443) Chronic lymphocytic leukemia ( 26956414 28165464) Creatinine levels ( 29124443) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 27424798) CV-A6-associated hand, foot, and mouth disease (severe vs mild) ( 32634583) Early spontaneous preterm birth ( 31477735) Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Estimated glomerular filtration rate ( 29124443) Evening vs. morning chronotype (sMEQ score) ( 32579418) Femur bone mineral density x serum urate levels interaction ( 34046847) Follicular lymphoma ( 25279986) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935 33627673) Glucose homeostasis traits ( 25524916) Granulocyte percentage of myeloid white cells ( 27863252) Graves' disease ( 22922229) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Hodgkin's lymphoma ( 29196614) IgE levels ( 22075330) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29235454 29617998 29785010 31959993) Itch intensity from mosquito bite ( 28199695) Keratinocyte cancer (MTAG) ( 31174203) Mean spheric corpuscular volume ( 32888494) Medication use (adrenergics, inhalants) ( 31015401) Medication use (thyroid preparations) ( 31015401) Monocyte count ( 32888494) Monocyte percentage of white cells ( 27863252 32888494) Mortality in sepsis ( 27639821) Mosquito bite size ( 28199695) Multiple sclerosis ( 24076602 31604244) Neutrophil percentage of granulocytes ( 27863252) Nodular sclerosis Hodgkin lymphoma ( 29196614) Obesity-related traits ( 23251661) Platelet distribution width ( 32888494) Renal function-related traits (BUN) ( 22797727) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Self-reported allergy ( 23817569) Serum urea levels ( 30808845) Squamous cell carcinoma ( 31174203) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966) Thyroid stimulating hormone levels ( 32769997) Triglyceride levels ( 32203549) Type 2 diabetes ( 24509480 25760438 28869590 30054458 30297969) Type 2 diabetes (young onset) and obesity ( 24465431) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Vitiligo ( 20410501 22951725 27723757) White matter integrity (bipolar disorder risk interaction) ( 23218918)
Novel Interacting Genes		2 novel interacting genes: AP2M1 FXR1
Interacting Genes		9 interacting genes: ACTN1 ATP5MF ATRAID MAGI1 MTNR1A SCRIB SHPRH TRIM21 VASP
Entrez ID		4026
HPRD ID		02828
Ensembl ID		ENSG00000145012
Uniprot IDs		B7Z871 B7Z8W0 B7ZLW0 Q93052
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamatergic Synapse Postsynapse Anchoring Junction Protein-containing Complex Organization Cell-cell Junction Cell Junction Cell Morphogenesis Cellular Component Assembly Synaptic Vesicle Endocytosis Presynaptic Endocytosis Negative Regulation Of Protein Metabolic Process Cell Projection Protein-containing Complex Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Protein-containing Complex Localization Regulation Of Receptor Internalization
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