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LORICRIN
Description
loricrin cornified envelope precursor protein
Image
No pdb structure
GO Annotations
Cellular Component
Cornified Envelope
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Structural Constituent Of Skin Epidermis
Biological Process
Cytoskeleton Organization
Peptide Cross-linking
Keratinocyte Differentiation
Keratinization
Pathways
Formation of the cornified envelope
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
GWAS
Novel Interacting Genes
8 novel interacting genes:
CSTA
EVPL
IVL
KRT1
PI3
SLC26A4-AS1
SPRR3
VIM
Interacting Genes
8 interacting genes:
CSTA
EVPL
IVL
KRT1
PI3
SLC26A4-AS1
SPRR3
VIM
Entrez ID
4014
HPRD ID
01070
Ensembl ID
ENSG00000203782
Uniprot IDs
P23490
PDB IDs
Enriched GO Terms of Interacting Partners
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Peptide Cross-linking
Cornified Envelope
Keratinocyte Differentiation
Keratinization
Epidermal Cell Differentiation
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Epithelial Cell Differentiation
Epidermis Development
Intermediate Filament
Endopeptidase Inhibitor Activity
Intermediate Filament Cytoskeleton
Protein Modification Process
Structural Constituent Of Skin Epidermis
Wound Healing
Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine
Intermediate Filament Organization
Copulation
Extracellular Exosome
Peptidase Inhibitor Activity
Peptidase Inhibitor Complex
Cell Differentiation
Cytosol
Regulation Of Antibacterial Peptide Production
Keratin Filament Binding
Structural Molecule Activity
Tissue Development
Lens Fiber Cell Development
Response To Wounding
Cellular Response To Muramyl Dipeptide
Bergmann Glial Cell Differentiation
Cellular Developmental Process
Protein Metabolic Process
Regulation Of Antimicrobial Humoral Response
Complement Activation, Lectin Pathway
Humoral Immune Response
Protein Heterotetramerization
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