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LAG3

Description lymphocyte activating 3
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Plasma Membrane
  • External Side Of Plasma Membrane
  • Cell Surface
  • Membrane
Molecular Function
  • Antigen Binding
  • Transmembrane Signaling Receptor Activity
  • Protein Binding
  • MHC Class II Protein Binding
Biological Process
  • Adaptive Immune Response
  • Plasmacytoid Dendritic Cell Activation
  • Immune System Process
  • Cell Surface Receptor Signaling Pathway
  • Negative Regulation Of Interleukin-2 Production
  • T Cell Activation
  • Natural Killer Cell Mediated Cytotoxicity
  • Innate Immune Response
  • Negative Regulation Of Regulatory T Cell Differentiation
  • Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
  • Regulation Of Immune Response
  • Negative Regulation Of T Cell Activation
Pathways
  • MHC class II antigen presentation
Drugs
  • Relatlimab
Diseases
GWAS
  • Blood protein levels ( 30072576)
Novel Interacting Genes 7 novel interacting genes: ALCAM CEBPZ CLEC4D CPAP GNAI2 KCNA1 UBE2E3
Interacting Genes 7 interacting genes: ALCAM CEBPZ CLEC4D CPAP GNAI2 KCNA1 UBE2E3
Entrez ID 3902
HPRD ID 01077
Ensembl ID ENSG00000089692
Uniprot IDs P18627
PDB IDs 7TZG 7TZH 7UM3 8SO3 8SR0 9BF9
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025