KLRC3

Description		killer cell lectin like receptor C3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Receptor Complex
	Molecular Function	Transmembrane Signaling Receptor Activity Carbohydrate Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Defense Response Regulation Of Natural Killer Cell Activation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Pathways
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Composite immunoglobulin trait (IgA/IgG) ( 28628107) Mean corpuscular volume ( 27863252)
Novel Interacting Genes		4 novel interacting genes: KLRD1 RHOU TSPAN15 TYROBP
Interacting Genes		4 interacting genes: KLRD1 RHOU TSPAN15 TYROBP
Entrez ID		3823
HPRD ID		04203
Ensembl ID		ENSG00000205810
Uniprot IDs		Q07444
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Activation Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Lymphocyte Mediated Immunity HLA-E Specific Inhibitory MHC Class Ib Receptor Activity MHC Class Ib Protein Binding, Via Antigen Binding Groove Leukocyte Mediated Immunity Stimulatory Killer Cell Immunoglobulin-like Receptor Signaling Pathway Innate Immune Response-activating Signaling Pathway Activation Of Innate Immune Response Positive Regulation Of Osteoclast Development Positive Regulation Of Microglial Cell Mediated Cytotoxicity Protein-macromolecule Adaptor Activity Positive Regulation Of Receptor Localization To Synapse Positive Regulation Of Macrophage Fusion Microglial Cell Activation Involved In Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune Effector Process Negative Regulation Of Transforming Growth Factor Beta1 Production Immune Response-regulating Cell Surface Receptor Signaling Pathway MHC Class I Protein Complex Binding Positive Regulation Of Innate Immune Response T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Positive Regulation Of Focal Adhesion Disassembly Protein Antigen Binding Regulation Of Osteoclast Development Tetraspanin-enriched Microdomain Negative Regulation Of T Cell Mediated Cytotoxicity Immune Response-activating Signaling Pathway Neutrophil Activation Involved In Immune Response Negative Regulation Of Long-term Synaptic Potentiation Actin Cytoskeleton Organization Negative Regulation Of Transforming Growth Factor Beta Production Immune Effector Process Immune Response-regulating Signaling Pathway Actin Filament-based Process Activation Of Immune Response Regulation Of Innate Immune Response Negative Regulation Of B Cell Proliferation Endocytosis Positive Regulation Of Defense Response Positive Regulation Of Protein Localization To Cell Surface Macrophage Activation Involved In Immune Response Positive Regulation Of Superoxide Anion Generation Plasma Membrane
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