KIR2DS4

Description		killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 (gene/pseudogene)
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Protein Binding MHC Class Ib Protein Binding
	Biological Process	Immune Response-regulating Signaling Pathway
Pathways		DAP12 interactions
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494)
Novel Interacting Genes		1 novel interacting genes: HLA-C
Interacting Genes		1 interacting genes: HLA-C
Entrez ID		3809
HPRD ID		05387
Ensembl ID		ENSG00000221957
Uniprot IDs		A0A0C4ZN05 A0A0C4ZN30 A0A1W2PR63 P43632 Q86VI6 Q8NHJ0
PDB IDs		3H8N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity MHC Class I Protein Complex Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Positive Regulation Of Natural Killer Cell Mediated Immunity Antigen Processing And Presentation Of Endogenous Antigen TAP Binding Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Binding Regulation Of T Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Cytotoxicity ER To Golgi Transport Vesicle Membrane Regulation Of Natural Killer Cell Mediated Immunity Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Phagocytic Vesicle Membrane Antigen Processing And Presentation Secretory Granule Membrane Regulation Of Leukocyte Mediated Cytotoxicity Recycling Endosome Membrane Regulation Of T Cell Mediated Immunity Receptor Ligand Activity Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Early Endosome Membrane Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Lymphocyte Mediated Immunity Regulation Of Adaptive Immune Response Positive Regulation Of Immune Effector Process Adaptive Immune Response Positive Regulation Of Innate Immune Response External Side Of Plasma Membrane Signaling Receptor Binding Regulation Of Innate Immune Response Positive Regulation Of Defense Response
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