ARF3

Description		ARF GTPase 3
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Vesicle-mediated Transport
Pathways		Synthesis of PIPs at the Golgi membrane COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heel bone mineral density ( 30598549)
Novel Interacting Genes		19 novel interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 CDK2 GGA1 GGA2 GGA3 GORAB KIF23 LINC00632 LNX1 PICK1 SCYL1 SLC2A4 SNCA SUMO2
Interacting Genes		19 interacting genes: APBA1 APBA2 APBA3 ARFIP1 ARFIP2 ATN1 CDK2 GGA1 GGA2 GGA3 GORAB KIF23 LINC00632 LNX1 PICK1 SCYL1 SLC2A4 SNCA SUMO2
Entrez ID		377
HPRD ID		00056
Ensembl ID		ENSG00000134287
Uniprot IDs		P61204
PDB IDs		6II6 8P50
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Protein Transport Intracellular Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Golgi Apparatus Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Cell Surface Membrane Curvature Sensor Activity Regulation Of Actin Nucleation Phospholipid Binding Golgi To Plasma Membrane Protein Transport Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Catabolic Process Trans-Golgi Network Golgi To Plasma Membrane Transport Perinuclear Region Of Cytoplasm Presynapse Amyloid-beta Binding Establishment Of Localization In Cell Intracellular Transport Ubiquitin Binding Post-Golgi Vesicle-mediated Transport Multicellular Organism Growth Trans-Golgi Network Membrane Small GTPase Binding Golgi Vesicle Transport Phosphatidylinositol Binding Protein Localization To Membrane Chemical Synaptic Transmission Synaptic Vesicle Vesicle-mediated Transport To The Plasma Membrane Trans-synaptic Signaling Monoamine Transport Phosphatidylinositol-4-phosphate Binding Synaptic Signaling Dendritic Spine Regulation Of Supramolecular Fiber Organization Cellular Localization Presynaptic Modulation Of Chemical Synaptic Transmission Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Retrograde Transport, Endosome To Golgi Locomotory Behavior
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