KCNC4

Description		potassium voltage-gated channel subfamily C member 4
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GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Dendrite Membrane Neuronal Cell Body Membrane Monoatomic Ion Channel Complex Presynaptic Membrane Axon Terminus Postsynaptic Membrane
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Gated Channel Activity Metal Ion Binding
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Chemical Synaptic Transmission Monoatomic Ion Transmembrane Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Dexfosfoserine
Diseases
GWAS		Gut microbiota (functional units) ( 27694959) Oropharynx cancer ( 27749845) Red blood cell count ( 32888494) Self-rated health ( 20707712)
Novel Interacting Genes		1 novel interacting genes: TNF
Interacting Genes		1 interacting genes: TNF
Entrez ID		3749
HPRD ID		08887
Ensembl ID		ENSG00000116396
Uniprot IDs		H7BZ66 Q03721
PDB IDs		1B4G 1B4I 1ZTN
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Chronic Inflammatory Response To Antigenic Stimulus Response To Gram-negative Bacterium Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Fractalkine Production Negative Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Positive Regulation Of Vitamin D Biosynthetic Process Response To 3,3',5-triiodo-L-thyronine Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Positive Regulation Of Neutrophil Activation Response To Transition Metal Nanoparticle Positive Regulation Of Synoviocyte Proliferation Positive Regulation Of Chronic Inflammatory Response Regulation Of Bile Acid Secretion Death Receptor Agonist Activity Response To Isolation Stress Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell Negative Regulation Of Bicellular Tight Junction Assembly Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Vascular Endothelial Growth Factor Production Positive Regulation Of Fever Generation Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Branching Involved In Salivary Gland Morphogenesis Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of Podosome Assembly Response To Macrophage Colony-stimulating Factor Negative Regulation Of Amyloid-beta Clearance Chronic Inflammatory Response Response To Fructose Endothelial Cell Apoptotic Process Positive Regulation Of Action Potential Regulation Of Neutrophil Activation Necroptotic Signaling Pathway Regulation Of Chronic Inflammatory Response Regulation Of Fever Generation Cellular Response To Nicotine Negative Regulation Of Cellular Respiration Positive Regulation Of Heat Generation Positive Regulation Of Interleukin-18 Production Negative Regulation Of Myelination Negative Regulation Of Vascular Wound Healing Positive Regulation Of Hepatocyte Proliferation Negative Regulation Of Oxidative Phosphorylation
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