ITGB6

Description		integrin subunit beta 6
Image
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Membrane Integrin Alphav-beta6 Complex Receptor Complex Anchoring Junction
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Inflammatory Response Immune Response Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Response To Wounding Response To Virus Gene Expression Cell Migration Cell Adhesion Mediated By Integrin Wound Healing Surfactant Homeostasis Skin Development Symbiont Entry Into Host Cell Lung Alveolus Development Phospholipid Homeostasis Hard Palate Development Bone Development Bronchiole Development Langerhans Cell Differentiation Enamel Mineralization Cellular Response To Ionizing Radiation Transforming Growth Factor Beta Production Cell-cell Adhesion
Pathways		Elastic fibre formation Molecules associated with elastic fibres Integrin cell surface interactions TGF-beta receptor signaling activates SMADs ECM proteoglycans
Drugs		PLN-74809
Diseases
GWAS		Appendicular lean mass ( 33097823) Asthma (childhood onset) ( 31036433) Eosinophil count ( 32888494) Haemorrhoidal disease ( 33888516) Hematocrit ( 32888494) Hemoglobin ( 32888494) Idiopathic membranous nephropathy ( 21323541) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Tourette syndrome ( 30818990) Type 2 diabetes ( 20418489) Waist circumference adjusted for body mass index ( 25673412)
Novel Interacting Genes		8 novel interacting genes: FHL2 FLNA FLNB FN1 ITGAV MAPK1 TGFB1 VTN
Interacting Genes		8 interacting genes: FHL2 FLNA FLNB FN1 ITGAV MAPK1 TGFB1 VTN
Entrez ID		3694
HPRD ID		00947
Ensembl ID		ENSG00000115221
Uniprot IDs		A0A087WXP3 B4E2B8 E9PEE8 P18564
PDB IDs		4UM8 4UM9 5FFG 5FFO 5NEM 5NER 5NET 5NEU 8TCG 9CZ7 9CZA 9CZD 9CZF
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Locomotion Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Focal Adhesion Endodermal Cell Differentiation Cellular Developmental Process Regulation Of Cell Migration Regulation Of Cell Motility Positive Regulation Of Cell Adhesion Regulation Of Locomotion Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Regulation Of Cell Adhesion Regulation Of Protein Metabolic Process Integrin-mediated Signaling Pathway Cell-matrix Adhesion Positive Regulation Of Integrin-mediated Signaling Pathway Cell Development Cell Migration Blood Microparticle Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell-substrate Adhesion Z Disc Identical Protein Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Signal Transduction Protein Activation Cascade Integrin Binding Cell Motility Cell-substrate Adhesion Regulation Of Integrin-mediated Signaling Pathway Regulation Of Intracellular Signal Transduction Developmental Process Positive Regulation Of Cellular Component Organization Cell Surface Receptor Signaling Pathway Regulation Of Vesicle-mediated Transport Cell Morphogenesis Cell Adhesion Mediated By Integrin Wound Healing, Spreading Of Cells Liver Regeneration Extracellular Matrix Binding Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell-substrate Adhesion Positive Regulation Of Protein Import Into Nucleus Animal Organ Development Regulation Of Cellular Component Organization Regulation Of Intracellular Transport Substrate Adhesion-dependent Cell Spreading
Tagcloud ?