IMPG1

Description		interphotoreceptor matrix proteoglycan 1
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Extracellular Region Extracellular Matrix Interphotoreceptor Matrix Cell Projection Cell Periphery
	Molecular Function	Extracellular Matrix Structural Constituent Hyaluronic Acid Binding Heparin Binding Chondroitin Sulfate Binding
	Biological Process	Visual Perception Extracellular Matrix Organization
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Hip circumference adjusted for BMI ( 34021172) Longevity ( 30294719) Menarche (age at onset) ( 25231870) QT interval ( 29213071) Response to fenofibrate (total cholesterol levels) ( 27002377) Sleep activity levels ( 33075057) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Novel Interacting Genes		1 novel interacting genes: WNT5A
Interacting Genes		1 interacting genes: WNT5A
Entrez ID		3617
HPRD ID		04186
Ensembl ID		ENSG00000112706
Uniprot IDs		A0A087WYL3 Q17R60
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemorepulsion Of Axon Postsynapse Assembly Primary Heart Field Specification Positive Regulation Of Protein Kinase C Activity Foam Cell Differentiation Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Protein Localization To Synapse Regulation Of Timing Of Anagen Hypophysis Morphogenesis Macrophage Derived Foam Cell Differentiation Convergent Extension Involved In Axis Elongation Receptor Tyrosine Kinase-like Orphan Receptor Binding Melanocyte Proliferation Chemoattraction Of Serotonergic Neuron Axon Negative Regulation Of Melanin Biosynthetic Process Mesodermal To Mesenchymal Transition Involved In Gastrulation Urinary Bladder Development Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Mammary Gland Branching Involved In Thelarche Positive Regulation Of Timing Of Anagen Chemoattractant Activity Involved In Axon Guidance Wnt Signaling Pathway, Calcium Modulating Pathway Negative Regulation Of Cell Proliferation In Midbrain Regulation Of Prostatic Bud Formation Paraxial Mesoderm Formation Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Optic Cup Formation Involved In Camera-type Eye Development Notochord Morphogenesis Olfactory Bulb Interneuron Development Hindgut Morphogenesis Cervix Development Convergent Extension Involved In Organogenesis Chemorepulsion Of Dopaminergic Neuron Axon Development Of Primary Male Sexual Characteristics Negative Regulation Of Prostatic Bud Formation Chemoattraction Of Axon Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Pericardium Morphogenesis Development Of Primary Sexual Characteristics Negative Regulation Of Axon Extension Involved In Axon Guidance Mesenchymal-epithelial Cell Signaling Positive Regulation Of Neuron Projection Arborization Midgut Development Atrial Septum Development Lateral Sprouting From An Epithelium Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Hematopoietic Stem Cell Proliferation Excitatory Synapse Assembly Thymocyte Apoptotic Process
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