IMPA2

Description		inositol monophosphatase 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Glucose-1-phosphatase Activity Inositol Monophosphate 1-phosphatase Activity Hydrolase Activity Protein Homodimerization Activity Metal Ion Binding Glycerol-2-phosphatase Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity
	Biological Process	Inositol Metabolic Process Inositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Response To Lithium Ion Phosphatidylinositol Phosphate Biosynthetic Process
Pathways		Synthesis of IP2, IP, and Ins in the cytosol
Drugs		Lithium cation Lithium citrate Lithium succinate Lithium carbonate
Diseases
GWAS		Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Hemoglobin ( 32888494) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744) Stroke ( 17434096)
Novel Interacting Genes		5 novel interacting genes: CCT6A HERPUD1 SLC44A3 TNFRSF14 UBA3
Interacting Genes		5 interacting genes: CCT6A HERPUD1 SLC44A3 TNFRSF14 UBA3
Entrez ID		3613
HPRD ID		09329
Ensembl ID		ENSG00000141401
Uniprot IDs		O14732
PDB IDs		2CZH 2CZI 2CZK 2DDK 2FVZ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Adaptive Immune Memory Response Endomitotic Cell Cycle NEDD8 Activating Enzyme Activity Lewy Body Core
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