IMPA1

Description		inositol monophosphatase 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Magnesium Ion Binding Glucose-6-phosphatase Activity Protein Binding Glucose-1-phosphatase Activity Inositol Monophosphate 1-phosphatase Activity Hydrolase Activity Manganese Ion Binding Lithium Ion Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Glycerol-2-phosphatase Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity Fructose-1-phosphatase Activity
	Biological Process	Inositol Metabolic Process Inositol Biosynthetic Process Phosphatidylinositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Phosphatidylinositol Phosphate Biosynthetic Process
Pathways		Synthesis of IP2, IP, and Ins in the cytosol
Drugs		Lithium cation L-Myo-Inositol-1-Phosphate Lithium citrate Lithium succinate Lithium carbonate
Diseases
GWAS		Ovarian cancer ( 23535730)
Novel Interacting Genes		3 novel interacting genes: CALB1 NXF1 S100B
Interacting Genes		3 interacting genes: CALB1 NXF1 S100B
Entrez ID		3612
HPRD ID		03641
Ensembl ID		ENSG00000133731
Uniprot IDs		A0A140VJL8 P29218
PDB IDs		1AWB 1IMA 1IMB 1IMC 1IMD 1IME 1IMF 2HHM 4AS4 6GIU 6GJ0 6ZK0 7VCE
Enriched GO Terms of Interacting Partners?		Metanephric Connecting Tubule Development Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Memory Metanephric Part Of Ureteric Bud Development Regulation Of Synaptic Plasticity Learning Or Memory Cognition Vitamin D Binding Metanephric Distal Convoluted Tubule Development Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Response To Anesthetic Response To Methylmercury Sympathetic Neuron Projection Extension Neuronal Cell Body Negative Regulation Of Skeletal Muscle Cell Differentiation Nuclear RNA Export Factor Complex Cuticular Plate Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Short-term Memory Metanephric Collecting Duct Development Metanephric Tubule Development Collecting Duct Development Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Metanephric Nephron Tubule Development Modulation Of Chemical Synaptic Transmission RAGE Receptor Binding S100 Protein Binding Nuclear Inclusion Body Transcription Export Complex Metanephric Epithelium Development Calyx Of Held Positive Regulation Of Myelination Response To Auditory Stimulus Calcium Ion Binding Nephron Tubule Development Regulation Of Skeletal Muscle Cell Differentiation Adaptive Thermogenesis Poly(A)+ MRNA Export From Nucleus Renal Tubule Development Retina Layer Formation Presynaptic Cytosol Postsynaptic Cytosol Astrocyte Differentiation Cochlea Development Long-term Memory Terminal Bouton Stereocilium Nervous System Process Regulation Of Myelination Tau Protein Binding
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