IFRD1

Description		interferon related developmental regulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Sarcoplasm
	Molecular Function
	Biological Process	Regulation Of Transcription By RNA Polymerase II Myoblast Fate Determination Striated Muscle Tissue Development Wnt Signaling Pathway Cell Differentiation Negative Regulation Of Axon Extension Muscle Cell Differentiation Skeletal Muscle Tissue Regeneration Fat Cell Differentiation Negative Regulation Of Collateral Sprouting Adipose Tissue Development
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (age of onset) ( 22959728) Dental caries (decayed, missing and filled teeth) ( 31533690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mortality in heart failure ( 20400778) Osteoarthritis (hip) ( 23989986) Refractive error ( 32231278)
Novel Interacting Genes		7 novel interacting genes: CSNK2A1 HDAC2 HDAC4 KLHL41 MYOD1 PDE4B RIT1
Interacting Genes		7 interacting genes: CSNK2A1 HDAC2 HDAC4 KLHL41 MYOD1 PDE4B RIT1
Entrez ID		3475
HPRD ID		04612
Ensembl ID		ENSG00000006652
Uniprot IDs		A4D0U1 O00458
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription By Competitive Promoter Binding Protein Lysine Deacetylase Activity Histone Deacetylase Activity, Hydrolytic Mechanism Sin3-type Complex Histone Deacetylase Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Cardiac Muscle Hypertrophy Muscle Hypertrophy Regulation Of Myoblast Proliferation DNA-binding Transcription Activator Activity Muscle System Process Histone Deacetylase Complex Regulation Of Cell Population Proliferation Regulation Of Myotube Differentiation Skeletal Muscle Cell Differentiation Positive Regulation Of Male Mating Behavior Promoter-specific Chromatin Binding Regulation Of Myoblast Differentiation Regulation Of Striated Muscle Cell Differentiation Cellular Response To Lipid Protein De-2-hydroxyisobutyrylase Activity Myoblast Fate Determination Negative Regulation Of Relaxation Of Cardiac Muscle Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Histone Deacetylase Binding Protein Lysine Delactylase Activity Fungiform Papilla Formation Skeletal Muscle Fiber Adaptation Negative Regulation Of Myoblast Proliferation Protein Decrotonylase Activity Histone Decrotonylase Activity Positive Regulation Of SnRNA Transcription By RNA Polymerase II Myotube Differentiation Involved In Skeletal Muscle Regeneration Regulation Of Muscle Cell Differentiation Positive Regulation Of Aggrephagy Hair Follicle Placode Formation Histone Binding Negative Regulation Of Gene Expression, Epigenetic Regulation Of Cell Differentiation Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Hydrolase Activity Protein Metabolic Process Protein Modification Process DNA-binding Transcription Factor Binding Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Cellular Response To Dopamine
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