NCKAP5

Description		NCK associated protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Microtubule Plus-end
	Molecular Function	Protein Binding
	Biological Process	Microtubule Bundle Formation Microtubule Depolymerization
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (survival time) ( 25649651) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive performance (processing speed) ( 31598132) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure x dichotomous lifestyle risk score interaction (1df test) ( 32227373) Diastolic blood pressure x dichotomous lifestyle risk score interaction (2df test) ( 32227373) Glaucoma (primary open-angle) ( 22419738) Gout (combined type) ( 32238385) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Height ( 20881960) Homeostasis model assessment of insulin resistance ( 33381925) Hypersomnia (HLA-DQB1*06:02 negative) ( 23646285) Initial pursuit acceleration ( 29064472) Iron status biomarkers (iron levels) ( 28334935) LDL cholesterol levels in HIV infection ( 33109212) Lingual gyrus volume ( 31530798) Optic disc size ( 31809533) PR interval ( 32439900) Rosacea symptom severity ( 29771307) Selective IgA deficiency ( 27723758) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Novel Interacting Genes		3 novel interacting genes: NCK1 NRIP1 VAV2
Interacting Genes		3 interacting genes: NCK1 NRIP1 VAV2
Entrez ID		344148
HPRD ID		19275
Ensembl ID		ENSG00000176771
Uniprot IDs		O14513
PDB IDs
Enriched GO Terms of Interacting Partners?		Lamellipodium Assembly Lamellipodium Organization Ovarian Follicle Rupture Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Cap-independent Translational Initiation Regulation Of Cellular Component Size Eukaryotic Initiation Factor EIF2 Binding Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cap-dependent Translational Initiation Signal Complex Assembly Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Cytoplasmic Translational Initiation Substrate-dependent Cell Migration, Cell Extension Signaling Receptor Binding Immune Response-regulating Signaling Pathway Cell Projection Assembly Regulation Of Translational Initiation In Response To Stress Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Translation In Response To Stress Immune Response-activating Signaling Pathway Plasma Membrane Bounded Cell Projection Assembly Activation Of Immune Response Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of PERK-mediated Unfolded Protein Response Protein Phosphatase Type 1 Complex Ovulation Nuclear Glucocorticoid Receptor Binding Regulation Of PERK-mediated Unfolded Protein Response Nuclear Retinoic Acid Receptor Binding Nuclear Retinoid X Receptor Binding Cytoskeletal Anchor Activity Regulation Of Translation In Response To Stress Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Enzyme-linked Receptor Protein Signaling Pathway Cell Activation Fc-epsilon Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Immune Response Ephrin Receptor Binding Signaling Receptor Complex Adaptor Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of Cytoplasmic Translation Negative Regulation Of T Cell Receptor Signaling Pathway Epidermal Growth Factor Receptor Binding Vascular Endothelial Growth Factor Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway
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